Anti-VPAC2 Rabbit mAb

PTM BIO

Anti-VPAC2 Rabbit mAb

5

ImmunoFluorescence, ImmunoCytoChemistry, ImmunoHistoChemistry Paraffin

IHC-P, ICC/IF

Antibody

Research Use Only

Monoclonal

JRMR-238

Unconjugated

Rabbit

IgG

Vasoactive intestinal polypeptide receptor 2

Human VIPR2 (Vasoactive Intestinal Polypeptide Receptor 2), also known as VPAC2, is a 60-70 kDa seven transmembrane glycoprotein receptor, which belongs to the G protein-coupled receptor 2 family of proteins. In its first extracellular region hormone receptor domain (aa 49-114) contains a mature chain, which has three N-linked glycosylation sites and a Cilia targeting signal , which is composed of and Arg -Composition of Asp-Tyr-Arg sequence. Human VIPR2 has relatively high homology with mouse and rat VIPR2. VIPR2 is mainly expressed in skeletal muscle, CD4+ T cells, smooth muscle cells, dendritic cells, liver precursor cells, single cells, synthetic cells and selective neurons. VIPR2 couples with CAMP-mediated signal transduction pathways, and binds VIP and pituitary adenase activating polypeptide (PACAP).

Stable for 12 months from date of receipt/reconstitution.

Human, Mouse, Rat

Protein A purified

Store at -20°C. Avoid freeze/thaw cycles.

12352203