Immunohistochemical staining of formalin-fixed and paraffin-embedded human mesothelioma tissue sections using anti-WT1 Rabbit Monoclonal Antibody (Clone RM516) at 1:100 dilution for 1 hr at room temperature.
Immunohistochemical staining of formalin-fixed and paraffin-embedded human mesothelioma tissue sections using anti-WT1 Rabbit Monoclonal Antibody (Clone RM516) at 1:100 dilution for 1 hr at room temperature.
anti-WT1 (human), Rabbit Monoclonal (RM516)
REV-31-1408-00
ApplicationsWestern Blot, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman
TargetWT1
Overview
- SupplierRevMAb Biosciences
- Product Nameanti-WT1 (human), Rabbit Monoclonal (RM516)
- Delivery Days Customer10
- Antibody SpecificityThis antibody reacts to human WT1 (Wilms tumor protein).
- ApplicationsWestern Blot, ImmunoHistoChemistry
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDRM516
- Gene ID7490
- Target nameWT1
- Target descriptionWT1 transcription factor
- Target synonymsAWT1; GUD; NPHS4; WAGR; Wilms tumor 1; Wilms tumor protein; WIT-2; WT33
- HostRabbit
- IsotypeIgG
- Protein IDP19544
- Protein NameWilms tumor protein
- Scientific DescriptionRecombinant Antibody. This antibody reacts to human WT1 (Wilms tumor protein). Isotype: Rabbit IgG. Immunogen: A peptide corresponding to residues near the N-terminus of human WT1. Applications: IHC, WB. WT1, a sporadic and familial pediatric kidney tumor, is genetically heterogeneous. Wilms tumor is associated with mutations of WT1, a zinc-finger transcription factor that is essential for the development of the metanephric kidney and the urogenital system. The WT1 gene is normally expressed in fetal kidney and mesothelium, and its expression has been suggested as a marker for Wilms tumor and mesothelioma. WT1 protein has been identified in proliferative mesothelial cells, malignant mesothelioma, ovarian carcinoma, gonadoblastoma, nephroblastoma and desmoplastic small round cell tumor. WT1 protein expression in mesothelial cells has become a reliable marker for the diagnosis of mesotheliomas. - WT1, a sporadic and familial pediatric kidney tumor, is genetically heterogeneous. Wilms tumor is associated with mutations of WT1, a zinc-finger transcription factor that is essential for the development of the metanephric kidney and the urogenital system. The WT1 gene is normally expressed in fetal kidney and mesothelium, and its expression has been suggested as a marker for Wilms tumor and mesothelioma. WT1 protein has been identified in proliferative mesothelial cells, malignant mesothelioma, ovarian carcinoma, gonadoblastoma, nephroblastoma and desmoplastic small round cell tumor. WT1 protein expression in mesothelial cells has become a reliable marker for the diagnosis of mesotheliomas.
- ReactivityHuman
- Storage Instruction-20°C
- UNSPSC12352203