Anti-XRCC3 [10F1/6]

Absolute Antibody

Anti-XRCC3 [10F1/6]

9

This antibody is specific for XRCC3 and does not cross-react with Rad51B, Rad51C, Rad51D, Rad51, or XRCC2 in Western blot analysis. XRCC3 is a protein involved in the homologous recombination repair (HRR) pathway in chromosomal fragmentations and deletion

WB: XRCC3 10F1/6 antibody was used to visualise XRCC3 on Western blots in multiple experiments (e.g. after previous gel filtration of infected pf9 cells; after immunoprecipitation with different antibodies and others) in a study on the RAD51 paralogs complexes and their role in genetic recombination (Masson et al., 2001). WB: Sage et al. (2010) used this antibody to visualise XRCC3 protein on Western blots from lysates of HCT116 cells in the experiments demonstrating engagement of Rad51 proteins in mtDNA maintenance. ICC/IF: XRCC3 protein was immunostained with XRCC3 10F1/6 antibody in HEK293 cells (some of the cells had been subjected to the ionising radiation) in an experiment investigating the exact role of XRCC3 in homologous recombination (Forget et al., 2004).

ImmunoFluorescence, Western Blot, ImmunoCytoChemistry

Research Use Only

Monoclonal

10F1/6

XRCC3

X-ray repair cross complementing 3

CMM6; DNA repair protein XRCC3; X-ray repair complementing defective repair in Chinese hamster cells 3; X-ray repair cross-complementing protein 3

Mouse

DNA repair protein XRCC3

This reformatted mouse antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques.

Human

-20°C,2°C to 8°C

12352203