anti-XRCC4 antibody

Arigo Biolaboratories

anti-XRCC4 antibody

23

ImmunoFluorescence, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Research Use Only

Polyclonal

Unconjugated

XRCC4

X-ray repair cross complementing 4

DNA repair protein XRCC4; SSMED; X-ray repair complementing defective repair in Chinese hamster cells 4

Rabbit

IgG

The protein encoded by this gene functions together with DNA ligase IV and the DNA-dependent protein kinase in the repair of DNA double-strand break by non-homologous end joining and the completion of V(D)J recombination events. The non-homologous end-joining pathway is required both for normal development and for suppression of tumors. This gene functionally complements XR-1 Chinese hamster ovary cell mutant, which is impaired in DNA double-strand breaks produced by ionizing radiation and restriction enzymes. Alternative transcription initiation and alternative splicing generates several transcript variants. [provided by RefSeq, Sep 2008]

Human, Mouse, Rat

-20°C

12352203