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alpha Smooth Muscle Actin antibody

Research Use Only
GTX100034
GeneTex
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse, Rat, Zebra Fish
TargetACTA2
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Overview

  • Supplier
    GeneTex
  • Product Name
    alpha Smooth Muscle Actin antibody
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    1.03 mg/ml
  • Conjugate
    Unconjugated
  • Formulation
    Liquid
  • Gene ID59
  • Target name
    ACTA2
  • Target description
    actin alpha 2, smooth muscle
  • Target synonyms
    actin, alpha 2, smooth muscle, aorta; actin, aortic smooth muscle; ACTSA; alpha-cardiac actin; cell growth-inhibiting gene 46 protein
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDP62736
  • Protein Name
    Actin, aortic smooth muscle
  • Scientific Description
    The protein encoded by this gene belongs to the actin family of proteins, which are highly conserved proteins that play a role in cell motility, structure and integrity. Alpha, beta and gamma actin isoforms have been identified, with alpha actins being a major constituent of the contractile apparatus, while beta and gamma actins are involved in the regulation of cell motility. This actin is an alpha actin that is found in skeletal muscle. Defects in this gene cause aortic aneurysm familial thoracic type 6. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Nov 2008]
  • Reactivity
    Human, Mouse, Rat, Zebra Fish
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • The down-regulation of XBP1, an unfolded protein response effector, promotes acute kidney injury to chronic kidney disease transition. Chen JH et al., 2022 Jun 28, J Biomed Sci
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  • H3K9me2 regulation of BDNF expression via G9a partakes in the progression of heart failure. Yan F et al., 2022 Apr 19, BMC Cardiovasc Disord
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  • Ameliorating role of microRNA-378 carried by umbilical cord mesenchymal stem cells-released extracellular vesicles in mesangial proliferative glomerulonephritis. Chen W et al., 2022 Mar 9, Cell Commun Signal
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  • Nuclear Receptor Interacting Protein-2 Mediates the Stabilization and Activation of beta-Catenin During Podocyte Injury. Hou Q et al., 2021, Front Cell Dev Biol
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  • Suppression of Inflammatory and Fibrotic Signals by Cinnamon (Cinnamomum cassia) and Cinnamaldehyde in Cyclophosphamide-Induced Overactive Bladder in Mice. Chen LL et al., 2021, Evid Based Complement Alternat Med
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  • Characterization of miR-34a-Induced Epithelial-Mesenchymal Transition in Non-Small Lung Cancer Cells Focusing on p53. Kawami M et al., 2021 Dec 9, Biomolecules
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  • Microsomal prostaglandin E synthase-1 is involved in the metabolic and cardiovascular alterations associated with obesity. Ballesteros-Martinez C et al., 2022 Jun, Br J Pharmacol
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  • The Role of Cell Proliferation and Extracellular Matrix Accumulation Induced by Food Additive Butylated Hydroxytoluene in Uterine Leiomyoma. Chiang YF et al., 2021 Aug 31, Nutrients
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  • Evaluation on epithelial-mesenchymal state and microRNAs focusing on isolated alveolar epithelial cells from bleomycin injured rat lung. Kawami M et al., 2021 Sep, Toxicology
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  • Unilateral Ureteral Obstruction for 28 Days in Rats Is Not Associated with Changes in Cardiac Function or Alterations in Mitochondrial Function. Prieto-Carrasco R et al., 2021 Jul 16, Biology (Basel)
    Read more