Anti-alpha-Tubulin Antibody, clone DM1A

Catalog number: 05-829
Brand: Merck
Packing: 200 ug
Price: € 623.00
Expected delivery time: 7 days

Product specifications for - Anti-alpha-Tubulin Antibody, clone DM1A

Product group: Antibodies
Category: Primary Antibodies
Application: Immunofluorescence
Application note: Immunofluorescence: (Breitling, F., 1986)
Host: Mouse
Target: TUBA1B
Target description: tubulin, alpha 1b
Clonality: Monoclonal
Isotype: IgG
  Research Use Only
UNSPSC: 12352203
Storage instructions: Stable for 1 year at -20-¦C from date of receipt. Handling Recommendations: Upon first thaw, and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20-¦C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance. Note: Variabillity in freezer temperatures below -20-¦C may cause glycerol containing solutions to become frozen during storage.
Scientific information: 
Scientific info: Microtubules are involved in a wide variety of cellular activities ranging from mitosis and transport events to cell movement and the maintenance of cell shape. Tubulin itself is a globular protein which consists of two polypeptides (alpha and beta tubulin). Alpha and beta tubulin dimers are assembled to 13 protofilaments that form a microtubule of 22 nm diameter. Tyrosine ligase ads a C-terminal tyrosin to monomeric alpha tubulin. Assembled microtubules can again be detyrosinated by a cytoskeleton associated carboxypeptidase. Detyrosinated alpha tubulin is referred to as Glu-tubulin. Another post-translational modification of detyrosinated alpha tubulin is C-terminal polyglutamylation which is characteristic for microtubules in neuronal cells and the mitotic spindle.
Clone ID: DM1A
Gene ID: 10376
Additional information: 
Synonyms: 05-829; Merck (Millipore)