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anti-BAFF (human), mAb (blocking) (4.62) (Biotin)

Research Use Only
AG-20B-0017B
AdipoGen Life Sciences
ApplicationsImmunoPrecipitation, ELISA, Neutralisation/Blocking
Product group Antibodies
ReactivityHuman
TargetTNFSF13B
Price on request
Packing Size
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Overview

  • Supplier
    AdipoGen Life Sciences
  • Product Name
    anti-BAFF (human), mAb (blocking) (4.62) (Biotin)
  • Delivery Days Customer
    10
  • Applications
    ImmunoPrecipitation, ELISA, Neutralisation/Blocking
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    4.62
  • Concentration
    0.5 mg/ml
  • Conjugate
    Biotin
  • Estimated Purity
    >95%
  • Gene ID10673
  • Target name
    TNFSF13B
  • Target description
    TNF superfamily member 13b
  • Target synonyms
    ApoL related ligand TALL-1; BAFF; B-cell-activating factor; B-lymphocyte stimulator; BLYS; CD257; delta BAFF; Delta4 BAFF; dendritic cell-derived TNF-like molecule; DTL; epididymis secretory sperm binding protein; TALL1; TALL-1; THANK; TNF and ApoL-related leukocyte expressed ligand 1; TNF homolog that activates apoptosis; TNFSF20; TNLG7A; tumor necrosis factor (ligand) superfamily, member 13b; tumor necrosis factor (ligand) superfamily, member 20; tumor necrosis factor ligand 7A; tumor necrosis factor ligand superfamily member 13B; tumor necrosis factor superfamily member 13b; tumor necrosis factor-like protein ZTNF4; ZTNF4
  • Host
    Rat
  • Isotype
    IgG2a
  • Scientific Description
    BAFF is a master regulator of peripheral B cell survival, and together with IL-6, promotes Ig class-switching and plasma cell differentiation. BAFF co-stimulates activated T cells. Increased levels of soluble BAFF have been detected in the serum of patients with various autoimmune diseases, such as Sjoegrens syndrome, rheumatoid arthritis, multiple sclerosis and systemic lupus erythematosus (SLE). Furthermore, BAFF is found in inflammatory sites in which there is lymphoid neogenesis. BAFF levels are elevated in patients with multiple myeloma and B cell chronic lymphoid leukemia (B-CCL). - Monoclonal Antibody. Recognizes human BAFF. Isotype: Rat IgG2a. Clone: 4.62. Applications: ELISA, FUNC (Blocking), IP. Liquid. In PBS containing 0.02% sodium azide. BAFF is a master regulator of peripheral B cell survival, and together with IL-6, promotes Ig class-switching and plasma cell differentiation. BAFF co-stimulates activated T cells. Increased levels of soluble BAFF have been detected in the serum of patients with various autoimmune diseases, such as Sjoegrens syndrome, rheumatoid arthritis, multiple sclerosis and systemic lupus erythematosus (SLE). Furthermore, BAFF is found in inflammatory sites in which there is lymphoid neogenesis. BAFF levels are elevated in patients with multiple myeloma and B cell chronic lymphoid leukemia (B-CCL).
  • Reactivity
    Human
  • Storage Instruction
    2°C to 8°C,-20°C
  • UNSPSC
    12352203