anti-BAFF (human), mAb (blocking) (4.62)
![Research Use Only](static/images/certificates/ruo.jpg)
AG-20B-0017
ApplicationsImmunoPrecipitation, ELISA, Neutralisation/Blocking
Product group Antibodies
ReactivityHuman
TargetTNFSF13B
Overview
- SupplierAdipoGen Life Sciences
- Product Nameanti-BAFF (human), mAb (blocking) (4.62)
- Delivery Days Customer10
- Antibody SpecificityRecognizes human BAFF.
- ApplicationsImmunoPrecipitation, ELISA, Neutralisation/Blocking
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone ID4.62
- Concentration1 mg/ml
- Estimated Purity>95%
- Gene ID10673
- Target nameTNFSF13B
- Target descriptionTNF superfamily member 13b
- Target synonymsApoL related ligand TALL-1; BAFF; B-cell-activating factor; B-lymphocyte stimulator; BLYS; CD257; delta BAFF; Delta4 BAFF; dendritic cell-derived TNF-like molecule; DTL; epididymis secretory sperm binding protein; TALL1; TALL-1; THANK; TNF and ApoL-related leukocyte expressed ligand 1; TNF homolog that activates apoptosis; TNFSF20; TNLG7A; tumor necrosis factor (ligand) superfamily, member 13b; tumor necrosis factor (ligand) superfamily, member 20; tumor necrosis factor ligand 7A; tumor necrosis factor ligand superfamily member 13B; tumor necrosis factor superfamily member 13b; tumor necrosis factor-like protein ZTNF4; ZTNF4
- HostRat
- IsotypeIgG2a
- Scientific DescriptionBAFF is a master regulator of peripheral B cell survival, and together with IL-6, promotes Ig class-switching and plasma cell differentiation. BAFF co-stimulates activated T cells. Increased levels of soluble BAFF have been detected in the serum of patients with various autoimmune diseases, such as Sjoegrens syndrome, rheumatoid arthritis, multiple sclerosis and systemic lupus erythematosus (SLE). Furthermore, BAFF is found in inflammatory sites in which there is lymphoid neogenesis. BAFF levels are elevated in patients with multiple myeloma and B cell chronic lymphoid leukemia (B-CCL). - Monoclonal Antibody. Recognizes human BAFF. Isotype: Rat IgG2a. Clone: 4.62. Applications: ELISA, FUNC (Blocking), IP. Liquid. In PBS containing 10% glycerol and 0.02% sodium azide. BAFF is a master regulator of peripheral B cell survival, and together with IL-6, promotes Ig class-switching and plasma cell differentiation. BAFF co-stimulates activated T cells. Increased levels of soluble BAFF have been detected in the serum of patients with various autoimmune diseases, such as Sjoegrens syndrome, rheumatoid arthritis, multiple sclerosis and systemic lupus erythematosus (SLE). Furthermore, BAFF is found in inflammatory sites in which there is lymphoid neogenesis. BAFF levels are elevated in patients with multiple myeloma and B cell chronic lymphoid leukemia (B-CCL).
- ReactivityHuman
- Storage Instruction2°C to 8°C,-20°C
- UNSPSC12352203