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Description
Catalog number
CAS No.
Clone ID
News
Vorige
Volgende
anti-Caspase-1 (p20) (human), mAb (Bally-1) (Biotin)
Catalog number:
AG-20B-0048B-C100
Brand:
AdipoGen Life Sciences
Packing:
100 ug
Price:
€ 425.00
Expected delivery time:
7 days
Quantity:
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General
References
Product specifications for - anti-Caspase-1 (p20) (human), mAb (Bally-1) (Biotin)
Overview:
Product group:
Antibodies
Category:
Primary Antibodies
Subcategory:
Other
Application:
Western Blot
Host:
Mouse
Target:
CASP1
Target description:
caspase 1
Clonality:
Monoclonal
Isotype:
IgG1
Properties:
Purity:
>95% (SDS-PAGE)
Datasheet:
Datasheet
Research Use Only
UNSPSC:
12352203
Concentration:
0.5 mg/ml
Form supplied:
Liquid. In PBS containing 0.02% sodium azide.
Storage instructions:
2-¦C to 8-¦C, -20-¦C
Scientific information:
Scientific info:
Caspase-1 is the best-described inflammatory caspase. It processes the cytokines interleukin-1beta (IL-1beta) and IL-18 and induces pyroptotic cell death. Caspase-1 is activated by multiprotein complexes called Inflammasomes in response to numerous stimuli that are detected through distinct inflammasomes. NLRC4 responds to cytosolic flagellin, murine NLRP1b responds to anthrax lethal toxin, AIM2 responds to cytosolic DNA and NLRP3 responds to a variety of agonists including crystals. - Monoclonal Antibody. Recognizes endogenous full-length and activated (p20 fragment) human caspase-1. Isotype: Mouse IgG1. Clone: Bally-1. Applications: WB. Liquid. In PBS containing 0.02% sodium azide. Caspase-1 is the best-described inflammatory caspase. It processes the cytokines interleukin-1beta (IL-1beta) and IL-18 and induces pyroptotic cell death. Caspase-1 is activated by multiprotein complexes called Inflammasomes in response to numerous stimuli that are detected through distinct inflammasomes. NLRC4 responds to cytosolic flagellin, murine NLRP1b responds to anthrax lethal toxin, AIM2 responds to cytosolic DNA and NLRP3 responds to a variety of agonists including crystals.
Clone ID:
Bally-1
Gene ID:
834
Swiss prot ID:
P29466
Safety information:
MSDS:
MSDS
Hazard information:
Non-hazardous
Additional information:
Synonyms:
AG-20B-0048B-C100; AdipoGen Life Sciences; CASP1 nirs variant 1; caspase 1, apoptosis-related cysteine peptidase; caspase-1; ICE; IL-1 beta-converting enzyme; IL1BC; IL1B-convertase; interleukin 1, beta, convertase; interleukin 1-B converting enzyme; Interleukin-1 beta convertase; Interleukin-1 beta-converting enzyme; P45
Liver X receptor beta activation induces pyroptosis of human and murine colon cancer cells: V. Derangere, et al.; Cell Death Differ. 21, 1914 (2014)
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Human monocytes engage an alternative inflammasome pathway: M.M. Gaidt, et al.; Immunity 44, 833 (2016)
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