anti-Caspase-3 antibody

Catalog number: ARG54938_100ug
Brand: Arigo Biolaboratories
Packing: 100 ug
Other sizes: Other size available
Price: € 482.00
Expected delivery time: 7 days

Product specifications for - anti-Caspase-3 antibody

Product group: Antibodies
Category: Primary Antibodies
Application: ICC/IF, ImmunoHistoChemistry, ImmunoPrecipitation, Western Blot
Application note: The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
Species: Human, Mouse, Rat
Host: Rabbit
Target: CASP3
Target description: caspase 3, apoptosis-related cysteine peptidase
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Molecular weight: 32 kDa
Datasheet: Datasheet
  Research Use Only
UNSPSC: 12352203
Form supplied: PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol
Storage instructions: For continuous use, store undiluted antibody at 2-8-¦C for up to a week. For long-term storage, aliquot and store at -20-¦C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Scientific information: 
Scientific info: This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein cleaves and activates caspases 6, 7 and 9, and the protein itself is processed by caspases 8, 9 and 10. It is the predominant caspase involved in the cleavage of amyloid-beta 4A precursor protein, which is associated with neuronal death in Alzheimer's disease. Alternative splicing of this gene results in two transcript variants that encode the same protein. [provided by RefSeq, Jul 2008]
Gene ID: 836
Swiss prot ID: P42574
Additional information: 
Synonyms: ARG54938; Arigo Biolaboratories; Caspase 3; CASP3; SCA-1; CPP32B; CPP32; protein Yama; procaspase3; cysteine protease CPP32; caspase-3; caspase 3, apoptosis-related cysteine protease; apopain; SREBP cleavage activity 1; PARP cleavage protease; CPP-32; CASP-3; caspase 3, apoptosis-related cysteine peptidase