anti-CD272 [BTLA] (human), mAb (ANC6E9)

Product specifications for - anti-CD272 [BTLA] (human), mAb (ANC6E9)

Overview:
Product group:	Antibodies
Category:	Primary Antibodies
Application:	ELISA; Flow Cytometry; Neutralisation/Blocking
Species:	Human
Host:	Mouse
Clonality:	Monoclonal
Isotype:	IgG1 Kappa

Properties:
Datasheet:	Datasheet
	Research Use Only
UNSPSC:	12352203
Form supplied:	50 mM Sodium Phosphate pH 7.5, 100 mM Potassium Chloride, 150mM NaCl, 0.5% Gentamicin sulfate
Storage instructions:	2-¦C to 8-¦C

Scientific information:
Scientific info:	Human CD272 (BTLA; B and T Lymphocyte Attenuator) is a member of the immunoglobulin superfamily and has sequence homology to PD-1 and CTLA-4. It is expressed on T and B lymphocytes and other hemopoetic lineages. Engagement of this molecule by its ligand CD270 (HVEM) can downregulate activated T and B cell responses. CD272 levels on antigen specific CD8+ T cells have been reported to decrease in viral specific, but not melanoma specific activated lines. Polymorphism of the CD272 molecule has been linked to rheumatoid arthritis. - Monoclonal Antibody. Isotype: Mouse IgG1kappa. Clone: ANC6E9. Applications: ELISA, FACS, FUNC (Blocking). 50 mM Sodium Phosphate pH 7.5, 100 mM Potassium Chloride, 150mM NaCl, 0.5% Gentamicin sulfate Human CD272 (BTLA; B and T Lymphocyte Attenuator) is a member of the immunoglobulin superfamily and has sequence homology to PD-1 and CTLA-4. It is expressed on T and B lymphocytes and other hemopoetic lineages. Engagement of this molecule by its ligand CD270 (HVEM) can downregulate activated T and B cell responses. CD272 levels on antigen specific CD8+ T cells have been reported to decrease in viral specific, but not melanoma specific activated lines. Polymorphism of the CD272 molecule has been linked to rheumatoid arthritis.
Clone ID:	ANC6E9

Scientific information:

Scientific info:

Human CD272 (BTLA; B and T Lymphocyte Attenuator) is a member of the immunoglobulin superfamily and has sequence homology to PD-1 and CTLA-4. It is expressed on T and B lymphocytes and other hemopoetic lineages. Engagement of this molecule by its ligand CD270 (HVEM) can downregulate activated T and B cell responses. CD272 levels on antigen specific CD8+ T cells have been reported to decrease in viral specific, but not melanoma specific activated lines. Polymorphism of the CD272 molecule has been linked to rheumatoid arthritis. - Monoclonal Antibody. Isotype: Mouse IgG1kappa. Clone: ANC6E9. Applications: ELISA, FACS, FUNC (Blocking). 50 mM Sodium Phosphate pH 7.5, 100 mM Potassium Chloride, 150mM NaCl, 0.5% Gentamicin sulfate Human CD272 (BTLA; B and T Lymphocyte Attenuator) is a member of the immunoglobulin superfamily and has sequence homology to PD-1 and CTLA-4. It is expressed on T and B lymphocytes and other hemopoetic lineages. Engagement of this molecule by its ligand CD270 (HVEM) can downregulate activated T and B cell responses. CD272 levels on antigen specific CD8+ T cells have been reported to decrease in viral specific, but not melanoma specific activated lines. Polymorphism of the CD272 molecule has been linked to rheumatoid arthritis.

Clone ID:

ANC6E9

Safety information:
Hazard information:	Non-hazardous

Additional information:
Synonyms:	ANC-272-020; Ancell Corporation

Find the product you need

News

Product specifications for - anti-CD272 [BTLA] (human), mAb (ANC6E9)

Login

Find the product you need

News

anti-CD272 [BTLA] (human), mAb (ANC6E9)

Product specifications for - anti-CD272 [BTLA] (human), mAb (ANC6E9)