anti-CD40L [CD154] (human), mAb (24-31)

Catalog number: ANC-353-020
Brand: Ancell Corporation
Packing: 100 ug
Price: € 200.00
Expected delivery time: 7 days
Quantity:

Product specifications for - anti-CD40L [CD154] (human), mAb (24-31)

Overview: 
Product group: Antibodies
Category: Primary Antibodies
Application: ELISA; Flow Cytometry; ImmunoHistoChemistry; Neutralisation/Blocking; Western Blot
Species: Human, Primate
Host: Mouse
Clonality: Monoclonal
Isotype: IgG1
Properties: 
Datasheet: Datasheet
  Research Use Only
UNSPSC: 12352203
Form supplied: 50 mM Sodium Phosphate pH 7.5, 100 mM Potassium Chloride, 150mM NaCl, 0.5% Gentamicin sulfate
Storage instructions: 2-¦C to 8-¦C
Scientific information: 
Scientific info: Human CD154 (CD40 ligand) is a member of the TNF family and is expressed on the surface of activated T cells. Interaction of CD154 and CD40 is essential for isotype switching in B cells. Known genetic defects that alter this interaction lead to impaired immune system function. CD154 has been shown to be hyperexpressed by B and T cells in SLE patients. CD154 has been reported to be expressed on vascular endothelial cells, smooth muscle cells and macrophages indicating a possible role for the CD40-CD154 immunoregulatory signaling mechanism during inflammation and immunity in atherogenesis. - Monoclonal Antibody. Isotype: Mouse IgG1. Clone: 24-31. Applications: ELISA, FACS, FUNC (Blocking), IHC, WB. 50 mM Sodium Phosphate pH 7.5, 100 mM Potassium Chloride, 150mM NaCl, 0.5% Gentamicin sulfate Human CD154 (CD40 ligand) is a member of the TNF family and is expressed on the surface of activated T cells. Interaction of CD154 and CD40 is essential for isotype switching in B cells. Known genetic defects that alter this interaction lead to impaired immune system function. CD154 has been shown to be hyperexpressed by B and T cells in SLE patients. CD154 has been reported to be expressed on vascular endothelial cells, smooth muscle cells and macrophages indicating a possible role for the CD40-CD154 immunoregulatory signaling mechanism during inflammation and immunity in atherogenesis.
Clone ID: 24-31
Safety information: 
Hazard information: Non-hazardous
Additional information: 
Synonyms: ANC-353-020; Ancell Corporation