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Description
Catalog number
CAS No.
Clone ID
News
Vorige
Volgende
anti-HMGB1 Neutralizing antibody [SQab20175] (low endotoxin)
Catalog number:
ARG66714_500ug
Brand:
Arigo Biolaboratories
Packing:
500 ug
Price:
€ 1490.00
Expected delivery time:
7 days
Quantity:
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General
Pictures
ELISA: 2 microg/ml dilution of reco...
ELISA: 2 microg/ml dilution of recombinant human HMGB1, bovine HMGB1 and recombinant human HMGB2 proteins (left to right) were coated onto ELISA plate. ARG66714 anti-HMGB1 Neutralizing antibody [SQab20175] (low endotoxin) at 1:3500 dilution were used for detecting HMGB1.
Flow Cytometry: HuH-7 cells (black)...
Flow Cytometry: HuH-7 cells (black) and HuH-7 shHMGB1 cells (red) stained with ARG66714 anti-HMGB1 Neutralizing antibody [SQab20175] (low endotoxin) at 1:500 dilution.
Neutralization assay: Mouse were in...
Neutralization assay: Mouse were injected with E. coli (3 x 10^9 CFU/kg) intraperitoneally. After 3 hours, antibodies (15 mg/kg) were given by i.p. injection. Mouse sera were collected 24 hours later and examined the level of IL6.
Neutralization assay: Cell culture ...
Neutralization assay: Cell culture medium from THP1 cells treated with 10 microg of mouse IgG, rhHMGB1 plus 10 microg of mouse IgG and rhHMGB1 plus 0.1 microg, 1 microg or 10 microg of ARG66714 anti-HMGB1 Neutralizing antibody [SQab20175] (low endotoxin) (left to right). TNF alpha concentration was tested by ARG80120 Human TNF alpha ELISA Kit.
Neutralization assay: Cell culture ...
Neutralization assay: Cell culture medium from Raw264.7 cells treated with 10 microg of mouse IgG, rmHMGB1 plus 10 microg of mouse IgG and rmHMGB1 plus 0.1 microg, 1 microg or 10 microg of ARG66714 anti-HMGB1 Neutralizing antibody [SQab20175] (low endotoxin) (left to right). TNF alpha concentration was tested by ARG80206 Mouse TNF alpha ELISA Kit.
Western blot: 100 ng of HMGB1 and H...
Western blot: 100 ng of HMGB1 and HMGB2 recombinant proteins stained with ARG66714 anti-HMGB1 Neutralizing antibody [SQab20175] (low endotoxin).
Product specifications for - anti-HMGB1 Neutralizing antibody [SQab20175] (low endotoxin)
Overview:
Product group:
Antibodies
Category:
Primary Antibodies
Application:
ELISA; Flow Cytometry; Neutralisation/Blocking; Western Blot
Species:
Human
Host:
Mouse
Target:
HMGB1
Target description:
high mobility group box 1
Clonality:
Monoclonal
Conjugation:
Unconjugated
Isotype:
IgM Kappa
Properties:
Datasheet:
Datasheet
Research Use Only
UNSPSC:
12352203
Storage instructions:
2-¦C to 8-¦C or -20-¦C
Scientific information:
Scientific info:
HMGB1 is a protein that belongs to the High Mobility Group-box superfamily. The encoded non-histone, nuclear DNA-binding protein regulates transcription, and is involved in organization of DNA. This protein plays a role in several cellular processes, including inflammation, cell differentiation and tumor cell migration. Multiple pseudogenes of this gene have been identified. Alternative splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, Sep 2015]
Clone ID:
SQab20175
Gene ID:
3146
Swiss prot ID:
P09429
Additional information:
Synonyms:
Inflammation research; ARG66714; Amphoterin; High mobility group protein 1; high mobility group protein B1; high-mobility group (nonhistone chromosomal) protein 1; HMG1; HMG-1; HMG3; SBP-1; Sulfoglucuronyl carbohydrate binding protein