Detection of endogenous mouse IL-1R2 with IL-1R2 (mouse), mAb (rec.) (Praxy-1-1) (AG-27B-0011). Method: In vitro-cultivated BMN (Neutrophils) (stimulated 24h with hydrocortisone) were stained with IL-1R2 (mouse), mAb (rec.) (Praxy-1) (thick green l
anti-IL-1R2 (mouse), mAb (rec.) (blocking) (Praxy-1-1)
AG-27B-0011
ApplicationsFlow Cytometry, ELISA, Neutralisation/Blocking
Product group Antibodies
ReactivityMouse
TargetIl1r2
Overview
- SupplierAdipoGen Life Sciences
- Product Nameanti-IL-1R2 (mouse), mAb (rec.) (blocking) (Praxy-1-1)
- Delivery Days Customer10
- Antibody SpecificityRecognizes mouse IL-1R2.
- ApplicationsFlow Cytometry, ELISA, Neutralisation/Blocking
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDPraxy-1-1
- Concentration1 mg/ml
- Estimated Purity>95%
- FormulationLiquid
- Gene ID16178
- Target nameIl1r2
- Target descriptioninterleukin 1 receptor, type II
- Target synonymsCD121 antigen-like family member B; CD121b; Il1; IL-1 receptor beta chain; IL-1 type II receptor; IL-1R-2; Il1r-2; IL-1R-beta; IL-1RT2; IL-1RT-2; interleukin-1 receptor beta; interleukin-1 receptor type 2
- HostMouse
- IsotypeIgG2b
- Protein IDP27931
- Protein NameInterleukin-1 receptor type 2
- Scientific DescriptionRecombinant Antibody. Recognizes mouse IL-1R2. Species cross-reactivity: Mouse. Clone: Praxy-1-1. Isotype: Mouse IgG2blambda. Applications: ELISA, FACS. Host: Purified from HEK 293 cell culture supernatant. Liquid. In PBS containing 10% glycerol and 0.02% sodium azide. The inflammatory actions of IL-1alpha and beta depend on their interaction with its receptor, IL-1R1, and can be negatively controlled by several inhibitors such as IL-1Ra, IL-1R type 2 (IL-1R2), SIGIRR and the soluble form of IL-1 receptor accessory protein (IL-1RAcP). IL-1R2 neutralizes IL-1 either as a surface decoy receptor or in a cleaved and secreted form. IL-1R2 is expressed on B cells, on neutrophils and on in vitro expanded human Tregs. - The inflammatory actions of IL-1alpha and beta depend on their interaction with its receptor, IL-1R1, and can be negatively controlled by several inhibitors such as IL-1Ra, IL-1R type 2 (IL-1R2), SIGIRR and the soluble form of IL-1 receptor accessory protein (IL-1RAcP). IL-1R2 neutralizes IL-1 either as a surface decoy receptor or in a cleaved and secreted form. IL-1R2 is expressed on B cells, on neutrophils and on in vitro expanded human Tregs.
- ReactivityMouse
- Storage Instruction-20°C,2°C to 8°C
- UNSPSC12352203