anti-Jagged-1 (human), mAb (J1G53-3)

AdipoGen Life Sciences

anti-Jagged-1 (human), mAb (J1G53-3)

10

Flow Cytometry, Western Blot, ELISA, ImmunoHistoChemistry

Research Use Only

Monoclonal

J1G53-3

1 mg/ml

JAG1

jagged canonical Notch ligand 1

AGS; AGS1; AHD; AWS; CD339; DCHE; HJ1; JAGL1; protein jagged-1

Mouse

IgG1

Jagged-1 is a ligand for multiple Notch receptors and involved in the mediation of Notch signaling. It is involved in cell-fate decisions during hematopoiesis. Is involved in early and late stages of mammalian cardiovascular development. Inhibits myoblast differentiation. Enhances fibroblast growth factor-induced angiogenesis (in vitro). Defects in Jagged-1 are the cause of Alagille syndrome type 1 (ALGS1) and tetralogy of Fallot (TOF). - Monoclonal Antibody. Recognizes human Jagged-1. Detects a band of ~180kDa by Western blot. Isotype: Mouse IgG1kappa. Clone: J1G53-3. Applications: ELISA, FACS, IHC, WB. Liquid. 0.2microm-filtered solution in PBS, pH 7.4. Contains no preservatives. Jagged-1 is a ligand for multiple Notch receptors and involved in the mediation of Notch signaling. It is involved in cell-fate decisions during hematopoiesis. Is involved in early and late stages of mammalian cardiovascular development. Inhibits myoblast differentiation. Enhances fibroblast growth factor-induced angiogenesis (in vitro). Defects in Jagged-1 are the cause of Alagille syndrome type 1 (ALGS1) and tetralogy of Fallot (TOF).

Human

2°C to 8°C,-20°C

12352203