Bio-Connect

anti-LTbetaR (mouse), mAb (3C8) (preservative free)

Research Use Only
AG-20B-0041PF
AdipoGen Life Sciences
ApplicationsNeutralisation/Blocking
Product group Antibodies
ReactivityMouse
TargetLtbr
Price on request
Packing Size
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Overview

  • Supplier
    AdipoGen Life Sciences
  • Product Name
    anti-LTbetaR (mouse), mAb (3C8) (preservative free)
  • Delivery Days Customer
    10
  • Antibody Specificity
    Recognizes mouse LTbetaR.
  • Applications
    Neutralisation/Blocking
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    3C8
  • Concentration
    1 mg/ml
  • Estimated Purity
    >95%
  • Formulation
    Liquid
  • Gene ID17000
  • Target name
    Ltbr
  • Target description
    lymphotoxin B receptor
  • Target synonyms
    AI256028; L; Ltar; LTbe; LT-beta receptor; LTbetaR; lymphotoxin-beta receptor; TN; Tnf; TNF-; TNF receptor-related protein; Tnfbr; TNFCR; TNFR; TNFR2-RP; TNF-R-III; TNFRrp; TNFR-RP; Tnfrsf3; tumor necrosis factor receptor superfamily member 3
  • Host
    Rat
  • Isotype
    IgG1
  • Protein IDP50284
  • Protein Name
    Tumor necrosis factor receptor superfamily member 3
  • Scientific Description
    Monoclonal Antibody. Recognizes mouse LTbetaR. Isotype: Rat IgG1kappa. Clone: 3C8. Applications: FUNC (Blocking). Liquid. In PBS The LTbetaR activates two different NF-kappaB pathways that lead to distinct patterns of gene induction, including selected chemokines and the cytokine BAFF, which is essential for the survival of mature B lymphocytes. LTbetaR activates the classical NF-kappaB (relA/p50) pathway, like the type 1 TNF receptor (TNFR1), that regulates proinflammatory genes, like the chemokine MIP1beta. However, LTbetaR, unlike TNFR1, also activates the processing of p100 to form RelB/p52 complexes, which activate genes involved in lymphoid organ formation and lymphocyte survival. - The LTbetaR activates two different NF-kappaB pathways that lead to distinct patterns of gene induction, including selected chemokines and the cytokine BAFF, which is essential for the survival of mature B lymphocytes. LTbetaR activates the classical NF-kappaB (relA/p50) pathway, like the type 1 TNF receptor (TNFR1), that regulates proinflammatory genes, like the chemokine MIP1beta. However, LTbetaR, unlike TNFR1, also activates the processing of p100 to form RelB/p52 complexes, which activate genes involved in lymphoid organ formation and lymphocyte survival.
  • Reactivity
    Mouse
  • Storage Instruction
    -20°C,2°C to 8°C
  • UNSPSC
    12352203