anti-LTbetaR (mouse), mAb (3C8) (preservative free)
AG-20B-0041PF
Overview
- SupplierAdipoGen Life Sciences
- Product Nameanti-LTbetaR (mouse), mAb (3C8) (preservative free)
- Delivery Days Customer10
- Antibody SpecificityRecognizes mouse LTbetaR.
- ApplicationsNeutralisation/Blocking
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone ID3C8
- Concentration1 mg/ml
- Estimated Purity>95%
- FormulationLiquid
- Gene ID17000
- Target nameLtbr
- Target descriptionlymphotoxin B receptor
- Target synonymsAI256028; L; Ltar; LTbe; LT-beta receptor; LTbetaR; lymphotoxin-beta receptor; TN; Tnf; TNF-; TNF receptor-related protein; Tnfbr; TNFCR; TNFR; TNFR2-RP; TNF-R-III; TNFRrp; TNFR-RP; Tnfrsf3; tumor necrosis factor receptor superfamily member 3
- HostRat
- IsotypeIgG1
- Protein IDP50284
- Protein NameTumor necrosis factor receptor superfamily member 3
- Scientific DescriptionMonoclonal Antibody. Recognizes mouse LTbetaR. Isotype: Rat IgG1kappa. Clone: 3C8. Applications: FUNC (Blocking). Liquid. In PBS The LTbetaR activates two different NF-kappaB pathways that lead to distinct patterns of gene induction, including selected chemokines and the cytokine BAFF, which is essential for the survival of mature B lymphocytes. LTbetaR activates the classical NF-kappaB (relA/p50) pathway, like the type 1 TNF receptor (TNFR1), that regulates proinflammatory genes, like the chemokine MIP1beta. However, LTbetaR, unlike TNFR1, also activates the processing of p100 to form RelB/p52 complexes, which activate genes involved in lymphoid organ formation and lymphocyte survival. - The LTbetaR activates two different NF-kappaB pathways that lead to distinct patterns of gene induction, including selected chemokines and the cytokine BAFF, which is essential for the survival of mature B lymphocytes. LTbetaR activates the classical NF-kappaB (relA/p50) pathway, like the type 1 TNF receptor (TNFR1), that regulates proinflammatory genes, like the chemokine MIP1beta. However, LTbetaR, unlike TNFR1, also activates the processing of p100 to form RelB/p52 complexes, which activate genes involved in lymphoid organ formation and lymphocyte survival.
- ReactivityMouse
- Storage Instruction-20°C,2°C to 8°C
- UNSPSC12352203