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Description
Catalog number
CAS No.
Clone ID
News
Vorige
Volgende
anti-MDA5 (human), mAb (Hely-1)
Catalog number:
AG-20B-0013-C100
Brand:
AdipoGen Life Sciences
Packing:
100 ug
Price:
€ 405.00
Expected delivery time:
7 days
Quantity:
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General
Product specifications for - anti-MDA5 (human), mAb (Hely-1)
Overview:
Product group:
Antibodies
Category:
Primary Antibodies
Application:
ELISA; ImmunoPrecipitation; Western Blot
Species:
Human
Host:
Mouse
Target:
IFIH1
Target description:
interferon induced with helicase C domain 1
Clonality:
Monoclonal
Isotype:
IgG1
Properties:
Purity:
>95% (SDS-PAGE)
Datasheet:
Datasheet
Research Use Only
UNSPSC:
12352203
Concentration:
1 mg/ml
Form supplied:
Liquid. In PBS containing 10% glycerol and 0.02% sodium azide.
Storage instructions:
2-¦C to 8-¦C, -20-¦C
Scientific information:
Scientific info:
Monoclonal Antibody. Recognizes human MDA5. Isotype: Mouse IgG1. Clone: Hely-1. Applications: ELISA, IP, WB. Liquid. In PBS containing 10% glycerol and 0.02% sodium azide. RIG-I and MDA5 are highly conserved helicases involved in the innate immune response to virus. RIG-I is a member of the DEAD-box RNA helicases and is activated by cytoplasmic dsRNA and 5-ppp RNA produced during the viral replication. The protein is characterized by a N-terminal region with two caspase recruitment domains (CARD) and a C-terminal region harboring potential ATP-dependent RNA helicase activity. RIG-1 recruits the CARD adaptor inducing IFN-beta (Cardif) in a CARD-CARD-dependent manner resulting in NF-kappaB and IRF3 activation. - RIG-I and MDA5 are highly conserved helicases involved in the innate immune response to virus. RIG-I is a member of the DEAD-box RNA helicases and is activated by cytoplasmic dsRNA and 5-ppp RNA produced during the viral replication. The protein is characterized by a N-terminal region with two caspase recruitment domains (CARD) and a C-terminal region harboring potential ATP-dependent RNA helicase activity. RIG-1 recruits the CARD adaptor inducing IFN-beta (Cardif) in a CARD-CARD-dependent manner resulting in NF-kappaB and IRF3 activation.
Clone ID:
Hely-1
Gene ID:
64135
Swiss prot ID:
Q9BYX4
Safety information:
MSDS:
MSDS
Hazard information:
Non-hazardous
Additional information:
Synonyms:
AG-20B-0013-C100; AdipoGen Life Sciences; AGS7; CADM-140 autoantigen; clinically amyopathic dermatomyositis autoantigen 140 kDa; DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide; helicard; helicase with 2 CARD domains; Hlcd; IDDM19; interferon-induced helicase C domain-containing protein 1; Interferon-induced with helicase C domain protein 1; MDA5; MDA-5; melanoma differentiation-associated gene 5; melanoma differentiation-associated protein 5; murabutide down-regulated protein; RIG-I-like receptor 2; RLR-2; RNA helicase-DEAD box protein 116; SGMRT1