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anti-MDA5 (human), mAb (Hely-1)

Catalog number: AG-20B-0013-C100
Brand: AdipoGen Life Sciences
Packing: 100 ug
Price: € 405.00
Expected delivery time: 7 days
Quantity:
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Product specifications for - anti-MDA5 (human), mAb (Hely-1)

Overview: 
Product group: Antibodies
Category: Primary Antibodies
Application: ELISA; ImmunoPrecipitation; Western Blot
Species: Human
Host: Mouse
Target: IFIH1
Target description: interferon induced with helicase C domain 1
Clonality: Monoclonal
Isotype: IgG1
Properties: 
Purity: >95% (SDS-PAGE)
Datasheet: Datasheet
  Research Use Only
UNSPSC: 12352203
Concentration: 1 mg/ml
Form supplied: Liquid. In PBS containing 10% glycerol and 0.02% sodium azide.
Storage instructions: 2-¦C to 8-¦C, -20-¦C
Scientific information: 
Scientific info: Monoclonal Antibody. Recognizes human MDA5. Isotype: Mouse IgG1. Clone: Hely-1. Applications: ELISA, IP, WB. Liquid. In PBS containing 10% glycerol and 0.02% sodium azide. RIG-I and MDA5 are highly conserved helicases involved in the innate immune response to virus. RIG-I is a member of the DEAD-box RNA helicases and is activated by cytoplasmic dsRNA and 5-ppp RNA produced during the viral replication. The protein is characterized by a N-terminal region with two caspase recruitment domains (CARD) and a C-terminal region harboring potential ATP-dependent RNA helicase activity. RIG-1 recruits the CARD adaptor inducing IFN-beta (Cardif) in a CARD-CARD-dependent manner resulting in NF-kappaB and IRF3 activation. - RIG-I and MDA5 are highly conserved helicases involved in the innate immune response to virus. RIG-I is a member of the DEAD-box RNA helicases and is activated by cytoplasmic dsRNA and 5-ppp RNA produced during the viral replication. The protein is characterized by a N-terminal region with two caspase recruitment domains (CARD) and a C-terminal region harboring potential ATP-dependent RNA helicase activity. RIG-1 recruits the CARD adaptor inducing IFN-beta (Cardif) in a CARD-CARD-dependent manner resulting in NF-kappaB and IRF3 activation.
Clone ID: Hely-1
Gene ID: 64135
Swiss prot ID: Q9BYX4
Safety information: 
MSDS: MSDS
Hazard information: Non-hazardous
Additional information: 
Synonyms: AG-20B-0013-C100; AdipoGen Life Sciences; AGS7; CADM-140 autoantigen; clinically amyopathic dermatomyositis autoantigen 140 kDa; DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide; helicard; helicase with 2 CARD domains; Hlcd; IDDM19; interferon-induced helicase C domain-containing protein 1; Interferon-induced with helicase C domain protein 1; MDA5; MDA-5; melanoma differentiation-associated gene 5; melanoma differentiation-associated protein 5; murabutide down-regulated protein; RIG-I-like receptor 2; RLR-2; RNA helicase-DEAD box protein 116; SGMRT1