anti-Neutrophils (mouse), mAb (blocking) (Nimp-R14) (Biotin)

Catalog number: AG-20B-0043B-C100
Brand: AdipoGen Life Sciences
Packing: 100 ug
Price: € 295.00
Expected delivery time: 7 days
Quantity:

Product specifications for - anti-Neutrophils (mouse), mAb (blocking) (Nimp-R14) (Biotin)

Overview: 
Product group: Antibodies
Category: Primary Antibodies
Subcategory: Other
Application: Flow Cytometry; ImmunoCytoChemistry; ImmunoHistoChemistry; Neutralisation/Blocking
Species: Mouse
Host: Rat
Clonality: Monoclonal
Conjugation: Biotin
Isotype: IgG2b
Properties: 
Purity: >95% (SDS-PAGE)
Datasheet: Datasheet
  Research Use Only
UNSPSC: 12352203
Concentration: 0.5 mg/ml
Form supplied: Liquid. In PBS containing 0.02% sodium azide.
Storage instructions: 2-¦C to 8-¦C, -20-¦C
Scientific information: 
Scientific info: Monoclonal Antibody. Recognizes mouse neutrophils (surface protein mouse Ly-6G) and may recognize Ly-6Chigh cells (inflammatory monocytes). Isotype: Rat IgG2b. Clone: Nimp-R14. Applications: FACS, FUNC (Blocking), ICC, IHC. Liquid. In PBS containing 0.02% sodium azide. Neutrophils are key components of the inflammatory response and as such contribute to the killing of microorganisms. In addition, recent evidence suggests their involvement in the development of the immune response. The Nimp-R14 mAb displays features of an optimal reagent allowing the selective depletion of mouse neutrophils in vivo. - Neutrophils are key components of the inflammatory response and as such contribute to the killing of microorganisms. In addition, recent evidence suggests their involvement in the development of the immune response. The Nimp-R14 mAb displays features of an optimal reagent allowing the selective depletion of mouse neutrophils in vivo.
Clone ID: Nimp-R14
Swiss prot ID: P35461
Safety information: 
MSDS: MSDS
Hazard information: Non-hazardous
Additional information: 
Synonyms: AG-20B-0043B-C100; AdipoGen Life Sciences; Ly-6G.1
Differentiation antigens on mouse eosinophils and neutrophils identified by monoclonal antibodies: A. Lopez, et al.; Brit. J. Haematol. 57, 489 (1984) Read more
Schistosoma mansoni: evidence that immunity in vaccinated and chronically infected CBA/Ca mice is sensitive to treatment with a monoclonal antibody that depletes cutaneous effector cells: D. McLaren, et al.; Parasite Immunol. 9, 667 (1987) Read more
Monocytes/macrophages rather than PMN are involved in early cartilage degradation in cationic immune complex arthritits in mice: P. Van Lent, et al.; J. Leukoc. Biol. 61, 267 (1997) Read more
Adenoviral vector-mediated overexpression of IL-4 in the knee joint of mice with collagen-induced arthritis prevents cartilage destruction: E. Lubberts, et al.; J. Immunol. 163, 4546 (1999) Read more
An immunomodulatory function for neutrophils during the induction of a CD4+ Th2 response in BALB/c mice infected with Leishmania major: F. Tacchini-Cottier, et al.; J. Immunol. 165, 628 (2000) Read more
A new mechanism for IL-5-dependent helminth control: neutrophil accumulation and neutrophil-mediated worm encapsulation in murine filariasis are abolished in the absence of IL-5: K.M. Al-Qaoud, et al.; Int. Immunol. 12, 899 (2000) Read more
Rapid recruitment of inflammatory monocytes is independent of neutrophil migration: R.B. Henderson, et al.; Blood 102, 328 (2003) Read more
Complement factor C5a mediates renal ischemia-reperfusion injury independent from neutrophils: B. de Vries, et al.; J. Immunol. 170, 3883 (2003) Read more
Absence of cross-reactivity between murine Ly-6C and Ly-6G: S. Nagendra, et al.; Cytom. A 58, 195 (2004) Read more
Activation of Toll-Like Receptor (TLR)2, TLR4, and TLR9 in the Mammalian Cornea Induces MyD88-Dependent Corneal Inflammation: A.C. Johnson, et al.; Invest. Ophthalmol. Vis. Sci. 46, 589 (2005) Read more