anti-NLRP3/NALP3, mAb (Cryo-2) (Biotin)

AdipoGen Life Sciences

anti-NLRP3/NALP3, mAb (Cryo-2) (Biotin)

10

ImmunoPrecipitation, Western Blot, ChIP Chromatin ImmunoPrecipitation, ImmunoCytoChemistry, ImmunoHistoChemistry

Research Use Only

Monoclonal

Cryo-2

1 mg/ml

Biotin

>95%

Mouse

IgG2b

Monoclonal Antibody. Recognizes mouse and human NLRP3/NALP3. Applications: IHC, IP, WB. Clone: Cryo-2. Isotype: Mouse IgG2b. Liquid. In PBS containing 0.02% Proclin300. The inflammasome is a multiprotein complex that mediates the activation of caspase-1, which promotes, amongst others, the secretion of the proinflammatory cytokines interleukin (IL)-1beta and IL-18. Members of the Nod-like receptor family, including NLRP3/NALP3, are critical components of the inflammasome that link danger-signals to caspase-1 activation. Defects in NLRP3 are the cause of familial cold autoinflammatory syndrome type 1 (FCAS1), Muckle-Wells syndrome (MWS) and of chronic infantile neurologic cutaneous and articular syndrome (CINCA). - The inflammasome is a multiprotein complex that mediates the activation of caspase-1, which promotes, amongst others, the secretion of the proinflammatory cytokines interleukin (IL)-1beta and IL-18. Members of the Nod-like receptor family, including NLRP3/NALP3, are critical components of the inflammasome that link danger-signals to caspase-1 activation. Defects in NLRP3 are the cause of familial cold autoinflammatory syndrome type 1 (FCAS1), Muckle-Wells syndrome (MWS) and of chronic infantile neurologic cutaneous and articular syndrome (CINCA).

Human, Mouse

2°C to 8°C,-20°C

12352203