Tech support
Shopping Cart
Login
Register
Forgot Password?
Products
Diagnostics
Suppliers
About us
Contact
+31 (0)26 326 4450
Find the product you need
Description
Catalog number
CAS No.
Clone ID
News
Vorige
Volgende
anti-NLRP3/NALP3 (mouse), mAb (Cryo-1)
Catalog number:
AG-20B-0006-C100
Brand:
AdipoGen Life Sciences
Packing:
100 ug
Price:
€ 425.00
Expected delivery time:
7 days
Quantity:
Spin Up
Spin Down
General
References
Product specifications for - anti-NLRP3/NALP3 (mouse), mAb (Cryo-1)
Overview:
Product group:
Antibodies
Category:
Primary Antibodies
Application:
Western Blot
Host:
Mouse
Target:
Nlrp3
Target description:
NLR family, pyrin domain containing 3
Clonality:
Monoclonal
Isotype:
IgG2b
Properties:
Purity:
>95% (SDS-PAGE)
Datasheet:
Datasheet
Research Use Only
UNSPSC:
12352203
Concentration:
1 mg/ml
Form supplied:
Liquid. In PBS containing 10% glycerol and 0.02% sodium azide.
Storage instructions:
2-¦C to 8-¦C, -20-¦C
Scientific information:
Scientific info:
Monoclonal Antibody. Recognizes mouse NLRP3/NALP3. Isotype: Mouse IgG2b. Clone: Cryo-1. Applications: WB. Liquid. In PBS containing 10% glycerol and 0.02% sodium azide. The inflammasome is a multiprotein complex that mediates the activation of caspase-1, which promotes, amongst others, the secretion of the proinflammatory cytokines interleukin (IL)-1beta and IL-18. Members of the Nod-like receptor family, including NLRP3/NALP3, are critical components of the inflammasome that link danger-signals to caspase-1 activation. Defects in NLRP3 are the cause of familial cold autoinflammatory syndrome type 1 (FCAS1), Muckle-Wells syndrome (MWS) and of chronic infantile neurologic cutaneous and articular syndrome (CINCA). - The inflammasome is a multiprotein complex that mediates the activation of caspase-1, which promotes, amongst others, the secretion of the proinflammatory cytokines interleukin (IL)-1beta and IL-18. Members of the Nod-like receptor family, including NLRP3/NALP3, are critical components of the inflammasome that link danger-signals to caspase-1 activation. Defects in NLRP3 are the cause of familial cold autoinflammatory syndrome type 1 (FCAS1), Muckle-Wells syndrome (MWS) and of chronic infantile neurologic cutaneous and articular syndrome (CINCA).
Clone ID:
Cryo-1
Gene ID:
216799
Swiss prot ID:
Q8R4B8
Safety information:
MSDS:
MSDS
Hazard information:
Non-hazardous
Additional information:
Synonyms:
AG-20B-0006-C100; AdipoGen Life Sciences; AGTAVPRL; AII/AVP; Cias1; cold autoinflammatory syndrome 1 protein homolog; cryopyrin; FCAS; FCU; mast cell maturation-associated-inducible protein 1; Mmig1; MWS; NACHT, LRR and PYD domains-containing protein 3; NACHT/LRR/pyrin domain-containing protein 3; NALP3; Pypaf1; PYRIN-containing APAF1-like protein 1
Nlrp6 promotes recovery after peripheral nerve injury independently of inflammasomes: E. Ydens, et al.; J. Neuroinfl. 12, 143 (2015)
Read more
See All