Detection of endogenous mouse Notch 1 or Notch 2 on resting and activated T cells with anti-Notch1 (mouse), mAb (22E5) (Prod. No. AG-20B-0051) and anti-Notch2, mAb (16F11) (Prod. No. AG-20B-0052), respectively. Method: CD4+ T cells from C57BL/6 mic
anti-Notch1 (mouse), mAb (22E5)
AG-20B-0051
Overview
- SupplierAdipoGen Life Sciences
- Product Nameanti-Notch1 (mouse), mAb (22E5)
- Delivery Days Customer10
- Antibody SpecificityRecognizes endogenous mouse Notch-1 receptor.
- ApplicationsFlow Cytometry
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone ID22E5
- Concentration1 mg/ml
- Estimated Purity>95%
- FormulationLiquid
- Gene ID18128
- Target nameNotch1
- Target descriptionnotch 1
- Target synonyms9930111A19Rik; lin; lin-12; major type A protein; Mi; Mis6; Motch A; mT14; N; N1; neurogenic locus notch homolog protein 1; Notch gene homolog 1; p300; Ta; Tan1
- HostRat
- IsotypeIgG2a
- Protein IDQ01705
- Protein NameNeurogenic locus notch homolog protein 1
- Scientific DescriptionMonoclonal Antibody. Recognizes endogenous mouse Notch-1 receptor. Isotype: Rat IgG2akappa. Clone: 2.20E+06. Applications: FACS. Liquid. In PBS containing 10% glycerol and 0.02% sodium azide. Notch signaling pathway regulates many different cell fate decisions in both vertebrate and invertebrate species. There are 5 canonical Notch ligands in mammals: Jagged-1, Jagged-2, DLL1, DLL3 and DLL4. These can bind to the four Notch receptors Notch 1-4. It is important for pattern formation during development such as neurogenesis, angiogenesis or myogenesis and regulates T cell development and stem cell maintenance. Notch signaling is also involved in cellular processes through-out adulthood. Signaling via Notch occurs between neighbouring cells and both the receptor and its ligands are transmembrane proteins. - Notch signaling pathway regulates many different cell fate decisions in both vertebrate and invertebrate species. There are 5 canonical Notch ligands in mammals: Jagged-1, Jagged-2, DLL1, DLL3 and DLL4. These can bind to the four Notch receptors Notch 1-4. It is important for pattern formation during development such as neurogenesis, angiogenesis or myogenesis and regulates T cell development and stem cell maintenance. Notch signaling is also involved in cellular processes through-out adulthood. Signaling via Notch occurs between neighbouring cells and both the receptor and its ligands are transmembrane proteins.
- ReactivityMouse
- Storage Instruction-20°C,2°C to 8°C
- UNSPSC12352203