anti-Notch2, mAb (16F11)

AdipoGen Life Sciences

anti-Notch2, mAb (16F11)

10

Flow Cytometry

Research Use Only

Monoclonal

16F11

1 mg/ml

>95%

Notch2

notch 2

AI853703; Motch B; N; N2; neurogenic locus notch homolog protein 2; Notch gene homolog 2

Rat

IgG1

Monoclonal Antibody. Recognizes human and mouse endogenous Notch-2 receptor. Isotype: Rat IgG1kappa. Clone: 16F11. Applications: FACS. Liquid. In PBS containing 10% glycerol and 0.02% sodium azide. Notch signaling pathway regulates many different cell fate decisions in both vertebrate and invertebrate species. There are 5 canonical Notch ligands in mammals: Jagged-1, Jagged-2, DLL1, DLL3 and DLL4. These can bind to the four Notch receptors Notch 1-4. It is important for pattern formation during development such as neurogenesis, angiogenesis or myogenesis and regulates T cell development and stem cell maintenance. Notch signaling is also involved in cellular processes through-out adulthood. Signaling via Notch occurs between neighbouring cells and both the receptor and its ligands are transmembrane proteins. - Notch signaling pathway regulates many different cell fate decisions in both vertebrate and invertebrate species. There are 5 canonical Notch ligands in mammals: Jagged-1, Jagged-2, DLL1, DLL3 and DLL4. These can bind to the four Notch receptors Notch 1-4. It is important for pattern formation during development such as neurogenesis, angiogenesis or myogenesis and regulates T cell development and stem cell maintenance. Notch signaling is also involved in cellular processes through-out adulthood. Signaling via Notch occurs between neighbouring cells and both the receptor and its ligands are transmembrane proteins.

Human, Mouse

2°C to 8°C,-20°C

12352203