anti-Pyrin (human), pAb (AL... | AG-25B-0020-C100 | AdipoGen - Bio-Connect

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Product specifications for - anti-Pyrin (human), pAb (AL196)

Overview:
Product group:	Antibodies
Category:	Primary Antibodies
Application:	ImmunoPrecipitation; Western Blot
Host:	Rabbit
Target:	MEFV
Target description:	MEFV, pyrin innate immunity regulator
Clonality:	Polyclonal

Properties:
Datasheet:	Datasheet
	Research Use Only
UNSPSC:	12352203
Concentration:	1 mg/ml
Form supplied:	Liquid. In PBS containing 10% glycerol and 0.02% sodium azide.
Storage instructions:	2-¦C to 8-¦C, -20-¦C

Scientific information:
Scientific info:	Polyclonal Antibody. Recognizes human pyrin. Source: Rabbit. Applications: IP, WB. Liquid. In PBS containing 10% glycerol and 0.02% sodium azide. Pyrin regulates inflammation by interacting with the cytoskeleton. Pyrin may direct the migration of white blood cells to sites of inflammation and stop or slow the inflammatory response when it is no longer needed. Defects in pyrin are the cause for Mediterranean fever. - Pyrin regulates inflammation by interacting with the cytoskeleton. Pyrin may direct the migration of white blood cells to sites of inflammation and stop or slow the inflammatory response when it is no longer needed. Defects in pyrin are the cause for Mediterranean fever.
Gene ID:	4210
Swiss prot ID:	O15553

Safety information:
MSDS:	MSDS
Hazard information:	Non-hazardous

Additional information:
Synonyms:	AG-25B-0020-C100; AdipoGen Life Sciences; FMF; marenostrin; Mediterranean fever; MEF; pyrin; TRIM20

The SPRY domain of Pyrin, mutated in familial Mediterranean fever patients, interacts with inflammasome components and inhibits proIL-1beta processing: S. Papin, et al.; Cell Death Differ. 14, 1457 (2007)

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