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ProductsBack/anti-RIG-I, mAb (Alme-1)
Western blot analysis of human RIG-I in HeLa cells by using RIG-I, mAb (Alme-1) (Prod. No. AG-20B-0009). Method: Cell extracts from HeLa cells either unstimulated (lane 1) or stimulated for 6h (lane 2), 16h (lane 3) or 24 h (lane 4) with Inte
Western blot analysis of human RIG-I in HeLa cells by using RIG-I, mAb (Alme-1) (Prod. No. AG-20B-0009). Method: Cell extracts from HeLa cells either unstimulated (lane 1) or stimulated for 6h (lane 2), 16h (lane 3) or 24 h (lane 4) with Inte
Western blot analysis of human RIG-I in HeLa cells by using RIG-I, mAb (Alme-1) (Prod. No. AG-20B-0009). Method: Cell extracts from HeLa cells either unstimulated (lane 1) or stimulated for 6h (lane 2), 16h (lane 3) or 24 h (lane 4) with Inte

anti-RIG-I, mAb (Alme-1)

Research Use Only
AG-20B-0009
AdipoGen Life Sciences
ApplicationsImmunoPrecipitation, Western Blot, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman, Mouse
TargetDDX58
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Overview

  • Supplier
    AdipoGen Life Sciences
  • Product Name
    anti-RIG-I, mAb (Alme-1)
  • Delivery Days Customer
    10
  • Antibody Specificity
    Recognizes human and mouse RIG-I.
  • Applications
    ImmunoPrecipitation, Western Blot, ImmunoHistoChemistry
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    Alme-1
  • Concentration
    1 mg/ml
  • Estimated Purity
    >95%
  • Formulation
    Liquid
  • Gene ID23586
  • Target name
    DDX58
  • Target description
    DExD/H-box helicase 58
  • Target synonyms
    antiviral innate immune response receptor RIG-I; DEAD (Asp-Glu-Ala-Asp) box polypeptide 58; DEAD box protein 58; DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide; probable ATP-dependent RNA helicase DDX58; retinoic acid-inducible gene 1 protein; retinoic acid-inducible gene I protein; RIG1; RIGI; RIG-I; RLR-1; RNA helicase RIG-I; SGMRT2
  • Host
    Mouse
  • Isotype
    IgG1
  • Protein IDO95786
  • Protein Name
    Probable ATP-dependent RNA helicase DDX58
  • Scientific Description
    Monoclonal Antibody. Recognizes human and mouse RIG-I. Isotype: Mouse IgG1. Clone: Alme-1. Applications: IHC, IP, WB. Liquid. In PBS containing 10% glycerol and 0.02% sodium azide. RIG-I and MDA5 are highly conserved helicases involved in the innate immune response to virus. RIG-I is a member of the DEAD-box RNA helicases and is activated by cytoplasmic dsRNA and 5-ppp RNA produced during the viral replication. The protein is characterized by a N-terminal region with two caspase recruitment domains (CARD) and a C-terminal region harboring potential ATP-dependent RNA helicase activity. RIG-I recruits the CARD adaptor inducing IFN-beta (Cardif) in a CARD-CARD-dependent manner resulting in NF-kappaB and IRF3 activation. - RIG-I and MDA5 are highly conserved helicases involved in the innate immune response to virus. RIG-I is a member of the DEAD-box RNA helicases and is activated by cytoplasmic dsRNA and 5-ppp RNA produced during the viral replication. The protein is characterized by a N-terminal region with two caspase recruitment domains (CARD) and a C-terminal region harboring potential ATP-dependent RNA helicase activity. RIG-I recruits the CARD adaptor inducing IFN-beta (Cardif) in a CARD-CARD-dependent manner resulting in NF-kappaB and IRF3 activation.
  • Reactivity
    Human, Mouse
  • Storage Instruction
    -20°C,2°C to 8°C
  • UNSPSC
    12352203