Anti-S-100 Protein Antibody, clone 15E2E2

Catalog number: MAB079-1
Brand: Merck
Packing: 100 ul
Price: € 527.00
Expected delivery time: 7 days

Product specifications for - Anti-S-100 Protein Antibody, clone 15E2E2

Product group: Antibodies
Category: Primary Antibodies
Application: Immunoprecipitation
Application note: Immunoprecipitation: A previous lot of this antibody was used in IP.Visualization of cellular and subcellular localization of S-100 protein using immunohistochemical techniques.Immunohistochemistry: A 1:100-200 dilution of a previous lot was used for paraffin embedded tissue sections. Optimal working dilutions must be determined by end user.
Host: Mouse
Clonality: Monoclonal
Isotype: IgG
  Research Use Only
UNSPSC: 12352203
Storage instructions: Stable for 1 year at 2-8-¦C from date of receipt.
Scientific information: 
Scientific info: S-100 protein is a member of the EF-hand calcium-binding protein superfamily that is widely distributed and conserved in the central nervous system of vertebrates. The protein exists in both heterodimeric and homodimeric forms. The two subunits of S-100 protein are the products of separate genes that are differentially expressed by various cells. The beta subunit is present in all S-100 positive cells and tumors. In contrast, the alpha subunit is detectable only in heart, skeletal muscle and brain. In addition to its calcium binding properties, S-100 protein has a high-affinity binding site for zinc and is involved in the regulation of protein phosphorylation in the brain. The protein apparently plays a role in cell differentiation and growth, cytoskeletal structure and function, and has been implicated in neuropathological diseases.
Clone ID: 15E2E2
Additional information: 
Synonyms: MAB079-1; Merck (Millipore)