Anti-Spectrin alpha chain (nonerythroid) Antibody, clone AA6

Catalog number: MAB1622
Brand: Merck
Packing: 50 ug
Price: On Request
Expected delivery time: 7 days

Product specifications for - Anti-Spectrin alpha chain (nonerythroid) Antibody, clone AA6

Product group: Antibodies
Category: Secondary Antibodies
Subcategory: Other
Application: Immunohistochemistry
Application note: Immunohistochemistry (IFA): A 1:200-1:400 dilution of a previous lot was used in immunohistochemistry.Does not work on paraffin sections.Optimal working dilutions must be determined by end user.Chromatin Immunopreciptiation: A previous lot of this antibody was used to immunoprecipitate Spectrin Alpha from chromatin-associated protein extracts derived from normal human, HeLa, FA-A, and transduced FA-A cells (McMahon, L.W., et al. (1999). J. Biological Chem. 274:32904-32908).
Host: Mouse
Clonality: Monoclonal
  Research Use Only
UNSPSC: 12352203
Storage instructions: Stable for 12 months at 2-8-¦C from date of receipt.
Scientific information: 
Scientific info: Non-erythroid Spectrin, also known as Fodrin, plays a role in stabilizing membrane structures, maintaining cell shape and linking the cytoskeleton to plasma membranes or intracellular vesicles. As one of the primary targets cleaved by activated caspases during apoptosis, the full-length ~240 kDa protein can be cleaved to yield an N-terminal product of ~150 kDa, and C-terminal products of ~120 and ~35 kDa.
Clone ID: AA6
Additional information: 
Synonyms: MAB1622; Merck (Millipore)