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Immunohistochemical staining of formalin fixed and paraffin embedded human Tonsil tissue section using anti-Stathmin rabbit monoclonal antibody (Clone RM350) at a 1:1000 dilution.
Immunohistochemical staining of formalin fixed and paraffin embedded human Tonsil tissue section using anti-Stathmin rabbit monoclonal antibody (Clone RM350) at a 1:1000 dilution.
Immunohistochemical staining of formalin fixed and paraffin embedded human Tonsil tissue section using anti-Stathmin rabbit monoclonal antibody (Clone RM350) at a 1:1000 dilution.

anti-Stathmin (human), Rabbit Monoclonal (RM350)

Research Use Only
REV-31-1236-00
RevMAb Biosciences
ApplicationsWestern Blot, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman
TargetSTMN1
Price on request
Packing Size
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Overview

  • Supplier
    RevMAb Biosciences
  • Product Name
    anti-Stathmin (human), Rabbit Monoclonal (RM350)
  • Delivery Days Customer
    5
  • Applications
    Western Blot, ImmunoHistoChemistry
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    RM350
  • Gene ID3925
  • Target name
    STMN1
  • Target description
    stathmin 1
  • Target synonyms
    C1orf215; Lag; LAP18; leukemia-associated phosphoprotein p18; metablastin; oncoprotein 18; OP18; phosphoprotein 19; phosphoprotein p19; PP17; PP19; PR22; prosolin; SMN; stathmin; stathmin 1/oncoprotein 18; testicular tissue protein Li 189; transmembrane protein C1orf215
  • Host
    Rabbit
  • Isotype
    IgG
  • Scientific Description
    Recombinant Antibody. This antibody reacts to human Stathmin. It may also react to mouse or rat Stathmin, as predicted by immunogen homology. Applications: WB, IHC. Source: Rabbit. Liquid. 50% Glycerol/PBS with 1% BSA and 0.09% sodium azide. Stathmin belongs to the stathmin family of genes. It encodes a ubiquitous cytosolic phosphoprotein proposed to function as an intracellular relay integrating regulatory signals of the cellular environment. Stathmin regulates microtubule dynamics by promoting depolymerization of microtubules and/or preventing polymerization of tubulin heterodimers. Upon entry into mitosis, microtubules polymerize to form the mitotic spindle, a cellular structure that is essential for accurate chromosome segregation and cell division. The microtubule-depolymerizing activity of stathmin is switched off at the onset of mitosis by phosphorylation to allow microtubule polymerization and assembly of the mitotic spindle. Phosphorylated stathmin has to be reactivated by dephosphorylation before cells exit mitosis and enter a new interphase. Stathmin is critically important for the formation of a normal mitotic spindle upon entry into mitosis and also for the regulation of the function of the mitotic spindle in the later stages of mitosis and for the timely exit from mitosis. - Stathmin belongs to the stathmin family of genes. It encodes a ubiquitous cytosolic phosphoprotein proposed to function as an intracellular relay integrating regulatory signals of the cellular environment. Stathmin regulates microtubule dynamics by promoting depolymerization of microtubules and/or preventing polymerization of tubulin heterodimers. Upon entry into mitosis, microtubules polymerize to form the mitotic spindle, a cellular structure that is essential for accurate chromosome segregation and cell division. The microtubule-depolymerizing activity of stathmin is switched off at the onset of mitosis by phosphorylation to allow microtubule polymerization and assembly of the mitotic spindle. Phosphorylated stathmin has to be reactivated by dephosphorylation before cells exit mitosis and enter a new interphase. Stathmin is critically important for the formation of a normal mitotic spindle upon entry into mitosis and also for the regulation of the function of the mitotic spindle in the later stages of mitosis and for the timely exit from mitosis.
  • Reactivity
    Human
  • Storage Instruction
    -20°C
  • UNSPSC
    12352203