anti-TRAIL-R1 (human), mAb (HS101) (preservative free)

AdipoGen Life Sciences

anti-TRAIL-R1 (human), mAb (HS101) (preservative free)

10

Recognizes human TRAIL-R1. Does not cross-react with human TRAIL-R2, -R3 or -R4.

Flow Cytometry, ImmunoPrecipitation, ImmunoCytoChemistry, Neutralisation/Blocking

Research Use Only

Monoclonal

HS101

1 mg/ml

>95%

Liquid

TNFRSF10A

TNF receptor superfamily member 10a

APO2; CD261; cytotoxic TRAIL receptor; death receptor 4; DR4; TNF-related apoptosis-inducing ligand receptor 1; TRAIL receptor 1; TRAILR1; TRAIL-R1; TRAILR-1; tumor necrosis factor receptor superfamily member 10A; tumor necrosis factor receptor superfamily member 10a variant 2; tumor necrosis factor receptor superfamily, member 10a

Mouse

IgG1

Tumor necrosis factor receptor superfamily member 10A

Monoclonal Antibody. Recognizes human TRAIL-R1. Does not cross-react with human TRAIL-R2, -R3 or -R4. Isotype: Mouse IgG1. Clone: HS101. Applications: FACS, FUNC (Blocking), ICC, IP. Liquid. In PBS containing 10% glycerol. TRAIL-R1 is a receptor for the cytotoxic ligand TRAIL. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Promotes the activation of NF-kappaB. - TRAIL-R1 is a receptor for the cytotoxic ligand TRAIL. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Promotes the activation of NF-kappaB.

Human

-20°C,2°C to 8°C

12352203