anti-TRAIL-R2 (human), mAb (HS201) (preservative free)
AG-20B-0023PF
ApplicationsFlow Cytometry, ImmunoPrecipitation, ImmunoCytoChemistry, Neutralisation/Blocking
Product group Antibodies
ReactivityHuman
TargetTNFRSF10B
Overview
- SupplierAdipoGen Life Sciences
- Product Nameanti-TRAIL-R2 (human), mAb (HS201) (preservative free)
- Delivery Days Customer10
- Antibody SpecificityRecognizes human TRAIL-R2. Does not cross-react with human TRAIL-R1, -R3 or -R4.
- ApplicationsFlow Cytometry, ImmunoPrecipitation, ImmunoCytoChemistry, Neutralisation/Blocking
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDHS201
- Concentration1 mg/ml
- Estimated Purity>95%
- FormulationLiquid
- Gene ID8795
- Target nameTNFRSF10B
- Target descriptionTNF receptor superfamily member 10b
- Target synonymsapoptosis inducing protein TRICK2A/2B; apoptosis inducing receptor TRAIL-R2; CD262; cytotoxic TRAIL receptor-2; death domain containing receptor for TRAIL/Apo-2L; death receptor 5; DR5; Fas-like protein; KILLER; KILLER/DR5; p53-regulated DNA damage-inducible cell death receptor(killer); TNF-related apoptosis-inducing ligand receptor 2; TRAILR2; TRAIL-R2; TRICK2; TRICK2A; TRICK2B; TRICKB; tumor necrosis factor receptor superfamily member 10B; tumor necrosis factor receptor superfamily, member 10b; tumor necrosis factor receptor-like protein ZTNFR9; ZTNFR9
- HostMouse
- IsotypeIgG1
- Protein IDO14763
- Protein NameTumor necrosis factor receptor superfamily member 10B
- Scientific DescriptionMonoclonal Antibody. Recognizes human TRAIL-R2. Does not cross-react with human TRAIL-R1, -R3 or -R4. Isotype: Mouse IgG1. Clone: HS201. Applications: FACS, FUNC (Blocking), ICC, IP. Liquid. In PBS containing 10% glycerol. TRAIL-R2 is a receptor for the cytotoxic ligand TRAIL. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Promotes the activation of NF-kappaB. - TRAIL-R2 is a receptor for the cytotoxic ligand TRAIL. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Promotes the activation of NF-kappaB.
- ReactivityHuman
- Storage Instruction-20°C,2°C to 8°C
- UNSPSC12352203