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Arginase 1 antibody - KO/KD Validated

Catalog number: GTX109242100
Brand: GeneTex
Packing: 100 ul
Other sizes: Other size available
Price: € 495.00
Expected delivery time: 10 days
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GTX109242 FACS Image
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GTX109242 IHC-P Image
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GTX109242 IHC-P Image
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GTX109242 IP Image
GTX109242 IP Image...
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GTX109242 WB Image
GTX109242 ELISA Image...
GTX109242 WB Image
GTX109242 ELISA Image...
GTX109242 ELISA Image
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Product specifications for - Arginase 1 antibody - KO/KD Validated

Overview: 
Product group: Antibodies
Category: Primary Antibodies
Application: ELISA; Flow Cytometry; ImmunoCytoChemistry; ImmunoFluorescence; ImmunoHistoChemistry; ImmunoHistoChemistry Frozen; ImmunoHistoChemistry Parrafin; ImmunoPrecipitation; Western Blot
Host: Rabbit
Target: ARG1
Target description: arginase 1
Clonality: Polyclonal
Isotype: IgG
Controle: Huh7 , HepG2 , mouse liver , rat liver
Properties: 
Datasheet: Datasheet
  Research Use Only
UNSPSC: 12352203
Concentration: 0.52 mg/ml
Storage instructions: 2-¦C to 8-¦C, -20-¦C or -80-¦C
Scientific information: 
Scientific info: Arginase catalyzes the hydrolysis of arginine to ornithine and urea. At least two isoforms of mammalian arginase exist (types I and II) which differ in their tissue distribution, subcellular localization, immunologic crossreactivity and physiologic function. The type I isoform encoded by this gene, is a cytosolic enzyme and expressed predominantly in the liver as a component of the urea cycle. Inherited deficiency of this enzyme results in argininemia, an autosomal recessive disorder characterized by hyperammonemia. [provided by RefSeq]
Gene ID: 383
Swiss prot ID: P05089
Additional information: 
Synonyms: GTX_citation; GTX109242; arginase, liver; arginase-1; liver-type arginase; type I arginase
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Anti-inflammatory immune skewing is atheroprotective: Apoe-/-FcgammaRIIb-/- mice develop fibrous carotid plaques. Harmon EY et al., 2014 Dec, J Am Heart Assoc Read more
Antisense oligonucleotide treatment enhances the recovery of acute lung injury through IL-10-secreting M2-like macrophage-induced expansion of CD4+ regulatory T cells. Guo Z et al., 2013 Apr 15, J Immunol Read more
Arterial dysfunction but maintained systemic blood pressure in cavin-1-deficient mice. Sward K et al., 2014, PLoS One Read more
Cyclic AMP is a key regulator of M1 to M2a phenotypic conversion of microglia in the presence of Th2 cytokines. Ghosh M et al., 2016 Jan 13, J Neuroinflammation Read more
Elevated pulmonary arterial pressure and altered expression of Ddah1 and Arg1 in mice lacking cavin-1/PTRF. Sward K et al., 2013 Jun, Physiol Rep Read more
Fat-laden macrophages modulate lobular inflammation in nonalcoholic steatohepatitis (NASH). Jindal A et al., 2015 Aug, Exp Mol Pathol Read more
Galectin-1 Reduces Neuroinflammation via Modulation of Nitric Oxide-Arginase Signaling in HIV-1 Transfected Microglia: a Gold Nanoparticle-Galectin-1 Nanoplex a Possible Neurotherapeutic? Aalinkeel R et al., 2017 Mar, J Neuroimmune Pharmacol Read more
Hepatocyte-secreted extracellular vesicles modify blood metabolome and endothelial function by an arginase-dependent mechanism. Royo F et al., 2017 Feb 17, Sci Rep Read more
HYCO-3, a dual CO-releaser/Nrf2 activator, reduces tissue inflammation in mice challenged with lipopolysaccharide. Motterlini R et al., 2019 Jan, Redox Biol Read more
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