Bax antibody [HL236]
GTX635715
Product group Antibodies
Overview
- SupplierGeneTex
- Product NameBax antibody [HL236]
- Delivery Days Customer9
- CertificationResearch Use Only
- Clone IDHL236
- Concentration1 mg/ml
- IsotypeIgG
- Scientific DescriptionThe protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein forms a heterodimer with BCL2, and functions as an apoptotic activator. This protein is reported to interact with, and increase the opening of, the mitochondrial voltage-dependent anion channel (VDAC), which leads to the loss in membrane potential and the release of cytochrome c. The expression of this gene is regulated by the tumor suppressor P53 and has been shown to be involved in P53-mediated apoptosis. Multiple alternatively spliced transcript variants, which encode different isoforms, have been reported for this gene. [provided by RefSeq, Jul 2008]
- Storage Instruction2°C to 8°C,-20°C
- UNSPSC12352203
References
- Cisplatin loaded multiwalled carbon nanotubes reverse drug resistance in NSCLC by inhibiting EMT. Qi Y et al., 2021 Jan 25, Cancer Cell IntRead more
- Inhibiting autophagy potentiates the antitumor efficacy of Euphorbia royleana for canine mammary gland tumors. Huang YY et al., 2020 Jun 12, BMC Vet ResRead more
- Let-7b-3p inhibits tumor growth and metastasis by targeting the BRF2-mediated MAPK/ERK pathway in human lung adenocarcinoma. Li Y et al., 2021 Apr, Transl Lung Cancer ResRead more