BDNF antibody [35928.11]
GTX10832
ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse
TargetBDNF
Overview
- SupplierGeneTex
- Product NameBDNF antibody [35928.11]
- Delivery Days Customer9
- Application Supplier NoteWB: 1-2 microg/ml. IHC-P: 8-25 microg/ml. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone ID35928.11
- ConjugateUnconjugated
- Gene ID627
- Target nameBDNF
- Target descriptionbrain derived neurotrophic factor
- Target synonymsabrineurin; ANON2; brain-derived neurotrophic factor; BULN2; neurotrophin
- HostMouse
- IsotypeIgG1
- Protein IDP23560
- Protein NameBrain-derived neurotrophic factor
- Scientific DescriptionBrain derived neurotrophic factor (BDNF) is a member of the neurotrophin family of growth factors that includes NGF, NT3, and NT4. All neurotrophins have six conserved cysteine residues and share a 55% sequence identity at the amino acid level. BDNF has been shown to enhance the survival and differentiation of several classes of neurons in vitro, including neural crest and placode-derived sensory neurons, dopaminergic neurons in the substantia nigra, basal forebrain cholinergic neurons, hippocampal neurons, and retinal ganglial cells. BDNF is expressed within peripheral ganglia and is not restricted to neuronal target fields, raising the possibility that BDNF has paracrine or even autocrine actions on neurons as well as non-neuronal cells.
- ReactivityHuman, Mouse
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Tau-Driven Neuronal and Neurotrophic Dysfunction in a Mouse Model of Early Tauopathy. Mazzaro N et al., 2016 Feb 17, J NeurosciRead more