Bio-Connect

BDNF antibody [35928.11]

GTX10832
GeneTex
ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse
TargetBDNF
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Overview

  • Supplier
    GeneTex
  • Product Name
    BDNF antibody [35928.11]
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1-2 microg/ml. IHC-P: 8-25 microg/ml. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    35928.11
  • Conjugate
    Unconjugated
  • Gene ID627
  • Target name
    BDNF
  • Target description
    brain derived neurotrophic factor
  • Target synonyms
    abrineurin; ANON2; brain-derived neurotrophic factor; BULN2; neurotrophin
  • Host
    Mouse
  • Isotype
    IgG1
  • Protein IDP23560
  • Protein Name
    Brain-derived neurotrophic factor
  • Scientific Description
    Brain derived neurotrophic factor (BDNF) is a member of the neurotrophin family of growth factors that includes NGF, NT3, and NT4. All neurotrophins have six conserved cysteine residues and share a 55% sequence identity at the amino acid level. BDNF has been shown to enhance the survival and differentiation of several classes of neurons in vitro, including neural crest and placode-derived sensory neurons, dopaminergic neurons in the substantia nigra, basal forebrain cholinergic neurons, hippocampal neurons, and retinal ganglial cells. BDNF is expressed within peripheral ganglia and is not restricted to neuronal target fields, raising the possibility that BDNF has paracrine or even autocrine actions on neurons as well as non-neuronal cells.
  • Reactivity
    Human, Mouse
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Tau-Driven Neuronal and Neurotrophic Dysfunction in a Mouse Model of Early Tauopathy. Mazzaro N et al., 2016 Feb 17, J Neurosci
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