BDNF antibody [35928.11]

Overview:
Product group:	Antibodies
Category:	Primary Antibodies
Application:	ImmunoHistoChemistry; ImmunoHistoChemistry Parrafin; Western Blot
Species:	Human
Host:	Mouse
Target:	BDNF
Target description:	brain derived neurotrophic factor
Clonality:	Monoclonal
Conjugation:	Unconjugated
Isotype:	IgG1
Controle:	human spinal cord

Scientific information:
Scientific info:	Brain derived neurotrophic factor (BDNF) is a member of the neurotrophin family of growth factors that includes NGF, NT3, and NT4. All neurotrophins have six conserved cysteine residues and share a 55% sequence identity at the amino acid level. BDNF has been shown to enhance the survival and differentiation of several classes of neurons in vitro, including neural crest and placode-derived sensory neurons, dopaminergic neurons in the substantia nigra, basal forebrain cholinergic neurons, hippocampal neurons, and retinal ganglial cells. BDNF is expressed within peripheral ganglia and is not restricted to neuronal target fields, raising the possibility that BDNF has paracrine or even autocrine actions on neurons as well as non-neuronal cells.
Clone ID:	35928.11
Gene ID:	627
Swiss prot ID:	P23560

Additional information:
Synonyms:	abrineurin; ANON2; brain-derived neurotrophic factor; BULN2; neurotrophin

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