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CD146 Antibody / MCAM / MUC18

Name: CD146 Antibody / MCAM / MUC18
SKU: ORB639799_B48
Availability: BackOrder

ORB639799

ApplicationsImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Product group Antibodies

ReactivityHuman

TargetMCAM

Overview

Supplier
Biorbyt
Product Name
CD146 Antibody / MCAM / MUC18
Delivery Days Customer
16
Application Supplier Note
Optimal dilution of the antibody should be determined by the researcher.
Applications
ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Applications Supplier
Immunohistochemistry (FFPE): 1-2ug/ml IHC-P
Certification
Research Use Only
Clonality
Monoclonal
Clone ID
MCAM/3046
Conjugate
Unconjugated
Gene ID4162
Target name
MCAM
Target description
melanoma cell adhesion molecule
Target synonyms
CD146; cell surface glycoprotein MUC18; cell surface glycoprotein P1H12; Gicerin; HEMCAM; melanoma adhesion molecule; melanoma-associated antigen A32; melanoma-associated antigen MUC18; MelCAM; METCAM; MUC18; S-endo 1 endothelial-associated antigen
Host
Mouse
Isotype
IgG1
Protein IDP43121
Protein Name
Cell surface glycoprotein MUC18
Scientific Description
The human Mel-CAM gene maps to chromosome 11q23 and encodes a trans-membrane glycoprotein, also designated MCAM, MUC 18 or CD146, that belongs to the immunoglobulin superfamily and functions as a Ca2+-independent cell adhesion molecule. Mel-CAM expression is restricted to advanced primary and metastatic melanomas and to cell lines of the neuroectodermal lineage, but not normal melanocytes. Mel-CAM is found on 80% of advanced primary human melanomas and correlates well with development of metastatic disease.
Reactivity
Human
Storage Instruction
-20°C,2°C to 8°C
UNSPSC
12352203