Overview
- SupplierGeneTex
- Product NameCD44 antibody
- Delivery Days Customer9
- CertificationResearch Use Only
- Concentration0.5 mg/ml
- IsotypeIgG
- Scientific DescriptionThe protein encoded by this gene is a cell-surface glycoprotein involved in cell-cell interactions, cell adhesion and migration. It is a receptor for hyaluronic acid (HA) and can also interact with other ligands, such as osteopontin, collagens, and matrix metalloproteinases (MMPs). This protein participates in a wide variety of cellular functions including lymphocyte activation, recirculation and homing, hematopoiesis, and tumor metastasis. Transcripts for this gene undergo complex alternative splicing that results in many functionally distinct isoforms, however, the full length nature of some of these variants has not been determined. Alternative splicing is the basis for the structural and functional diversity of this protein, and may be related to tumor metastasis. [provided by RefSeq]
- Storage Instruction2°C to 8°C,-20°C
- UNSPSC12352203
References
- A high-throughput pipeline for validation of antibodies. Sikorski K et al., 2018 Nov, Nat MethodsRead more
- A Metabolic Basis for Endothelial-to-Mesenchymal Transition. Xiong J et al., 2018 Feb 15, Mol CellRead more
- A potent indolylquinoline alleviates growth of human lung cancer cell tumorspheres. Ni YL et al., 2017 Oct, ApoptosisRead more
- A set of cancer stem cell homing peptides associating with the glycan moieties of glycosphingolipids. Su YH et al., 2018 Apr 17, OncotargetRead more
- Aspirin counteracts cancer stem cell features, desmoplasia and gemcitabine resistance in pancreatic cancer. Zhang Y et al., 2015 Apr 30, OncotargetRead more
- CD44-specific nanoparticles for redox-triggered reactive oxygen species production and doxorubicin release. Lin CW et al., 2016 Apr 15, Acta BiomaterRead more
- Combination Twist1 and CA15-3 in axillary lymph nodes for breast cancer prognosis. Jiang X et al., 2017 Mar, Mol Med RepRead more
- Comprehensive proteome quantification reveals NgBR as a new regulator for epithelial-mesenchymal transition of breast tumor cells. Zhao B et al., 2015 Jan 1, J ProteomicsRead more
- Differential protein expression between chondrogenic differentiated MSCs, undifferentiated MSCs and adult chondrocytes derived from Oryctolagus cuniculus in vitro. Tay LX et al., 2014, Int J Med SciRead more
- Elucidation of the mechanism underlying CD44v6-induced transformation of IEC-6 normal intestinal epithelial cells. Chung SY et al., 2020 Jan, J Cell PhysiolRead more