CDC42 Rabbit mAb

Catalog number: A19028_50ul
Brand: ABClonal
Packing: 50 ul
Other sizes: Other sizes available
Price: € 287.00
Expected delivery time: 12 days
Quantity:

Product specifications for - CDC42 Rabbit mAb

Overview: 
Product group: Antibodies
Category: Primary Antibodies
Properties: 
Datasheet: Datasheet
  Research Use Only
UNSPSC: 12352203
Storage instructions: Store at -20-¦C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Scientific information: 
Scientific info: The protein encoded by this gene is a small GTPase of the Rho-subfamily, which regulates signaling pathways that control diverse cellular functions including cell morphology, migration, endocytosis and cell cycle progression. This protein is highly similar to Saccharomyces cerevisiae Cdc 42, and is able to complement the yeast cdc42-1 mutant. The product of oncogene Dbl was reported to specifically catalyze the dissociation of GDP from this protein. This protein could regulate actin polymerization through its direct binding to Neural Wiskott-Aldrich syndrome protein (N-WASP), which subsequently activates Arp2/3 complex. Alternative splicing of this gene results in multiple transcript variants. Pseudogenes of this gene have been identified on chromosomes 3, 4, 5, 7, 8 and 20. [provided by RefSeq, Apr 2013]
Additional information: 
Synonyms: RabMabs; Cytoskeleton Regulation