More than 130 suppliers
ISO certified
In-house tech support
we Connect you
Bio-Connect
ProductsBack/Desmoglein 3 Antibody / DSG3

Desmoglein 3 Antibody / DSG3

ORB639790
Biorbyt
ApplicationsImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman
TargetDSG3
Sign in to order and to see your custom pricing.
Large volume orders?
Order with a bulk request
More than 130 suppliers
ISO certified
In-house tech support

Overview

  • Supplier
    Biorbyt
  • Product Name
    Desmoglein 3 Antibody / DSG3
  • Delivery Days Customer
    16
  • Application Supplier Note
    Optimal dilution of the antibody should be determined by the researcher.
  • Applications
    ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Applications Supplier
    Immunohistochemistry (FFPE): 1-2ug/ml IHC-P
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    DSG3/2839
  • Conjugate
    Unconjugated
  • Gene ID1830
  • Target name
    DSG3
  • Target description
    desmoglein 3
  • Target synonyms
    130 kDa pemphigus vulgaris antigen; ABOLM; cadherin family member 6; CDHF6; desmoglein-3; PVA
  • Host
    Mouse
  • Isotype
    IgG1
  • Protein IDP32926
  • Protein Name
    Desmoglein-3
  • Scientific Description
    Recognizes a protein of 130kDa, identified as Desmoglein-3 (DSG3). This MAb is highly specific to Desmoglein-3 and does not cross-react with other members of the Desmoglein-family. DSG3 is a calcium-binding transmembrane glycoprotein component of desmosomes in vertebrate epithelial cells. Research has shown that DSG3 has a very high sensitivity (80%) and specificity (100%) in recognizing squamous cell carcinoma (SqCC). Therefore, DSG3 is considered a very important marker for lung SqCC and can be a useful ancillary marker to separate SqCC from other subtypes of lung cancer. Moreover, studies have shown that DSG3 expression in lung SqCC may indicate a poor prognosis.
  • Reactivity
    Human
  • Storage Instruction
    -20°C,2°C to 8°C
  • UNSPSC
    12352203