Dopamine beta Hydroxylase antibody [HL1163]

GeneTex

Dopamine beta Hydroxylase antibody [HL1163]

9

WB: 1:500-1:3000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

ImmunoFluorescence, Western Blot, ImmunoCytoChemistry

Research Use Only

Monoclonal

HL1163

1 mg/ml

Unconjugated

Liquid

DBH

dopamine beta-hydroxylase

DBM; dopamine beta-hydroxylase; dopamine beta-hydroxylase (dopamine beta-monooxygenase); ORTHYP1

Rabbit

IgG

Dopamine beta-hydroxylase

The protein encoded by this gene is an oxidoreductase belonging to the copper type II, ascorbate-dependent monooxygenase family. The encoded protein, expressed in neuroscretory vesicles and chromaffin granules of the adrenal medulla, catalyzes the conversion of dopamine to norepinephrine, which functions as both a hormone and as the main neurotransmitter of the sympathetic nervous system. The enzyme encoded by this gene exists exists in both soluble and membrane-bound forms, depending on the absence or presence, respectively, of a signal peptide. Mutations in this gene cause dopamine beta-hydroxylate deficiency in human patients, characterized by deficits in autonomic and cardiovascular function, including hypotension and ptosis. Polymorphisms in this gene may play a role in a variety of psychiatric disorders. [provided by RefSeq, Aug 2017]

Human

-20°C or -80°C,2°C to 8°C

12352203