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Description
Catalog number
CAS No.
Clone ID
News
Vorige
Volgende
Girdin (phospho Ser1417) antibody - Orthogonal Validated
Catalog number:
GTX55363
Brand:
GeneTex
Packing:
100 ul
Price:
€ 515.00
Expected delivery time:
10 days
Quantity:
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General
Pictures
GTX55363 IHC-P Image
GTX55363 IHC-P Image...
GTX55363 IHC-P Image
GTX55363 IHC-P Image
Product specifications for - Girdin (phospho Ser1417) antibody - Orthogonal Validated
Overview:
Product group:
Antibodies
Category:
Primary Antibodies
Application:
ImmunoHistoChemistry; ImmunoHistoChemistry Parrafin
Host:
Rabbit
Target:
CCDC88A
Target description:
coiled-coil domain containing 88A
Clonality:
Polyclonal
Isotype:
IgG
Properties:
Datasheet:
Datasheet
Research Use Only
UNSPSC:
12352203
Concentration:
1 mg/ml
Storage instructions:
2-¦C to 8-¦C, -20-¦C or -80-¦C
Scientific information:
Scientific info:
This gene encodes a member of the Girdin family of coiled-coil domain containing proteins. The encoded protein is an actin-binding protein that is activated by the serine/threonine kinase Akt and plays a role in cytoskeleton remodeling and cell migration. The encoded protein also enhances Akt signaling by mediating phosphoinositide 3-kinase (PI3K)-dependent activation of Akt by growth factor receptor tyrosine kinases and G protein-coupled receptors. Increased expression of this gene and phosphorylation of the encoded protein may play a role in cancer metastasis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011]
Gene ID:
55704
Swiss prot ID:
Q3V6T2
Additional information:
Synonyms:
GTX55363; Akt phosphorylation enhancer; AKT-phosphorylation enhancer; APE; Coiled-coil domain-containing protein 88A; g alpha-interacting vesicle-associated protein; Girders of actin filament; girders of actin filaments; girdin; GIV; GRDN; HkRP1; Hook-related protein 1; KIAA1212; PEHO; PEHOL