Girdin (phospho Ser1417) antibody... | GTX55363 | GeneTex - Bio-Connect

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GTX55363 IHC-P Image

GTX55363 IHC-P Image...

Product specifications for - Girdin (phospho Ser1417) antibody - Orthogonal Validated

Overview:
Product group:	Antibodies
Category:	Primary Antibodies
Application:	ImmunoHistoChemistry; ImmunoHistoChemistry Parrafin
Host:	Rabbit
Target:	CCDC88A
Target description:	coiled-coil domain containing 88A
Clonality:	Polyclonal
Isotype:	IgG

Properties:
Datasheet:	Datasheet
	Research Use Only
UNSPSC:	12352203
Concentration:	1 mg/ml
Storage instructions:	2-¦C to 8-¦C, -20-¦C or -80-¦C

Scientific information:
Scientific info:	This gene encodes a member of the Girdin family of coiled-coil domain containing proteins. The encoded protein is an actin-binding protein that is activated by the serine/threonine kinase Akt and plays a role in cytoskeleton remodeling and cell migration. The encoded protein also enhances Akt signaling by mediating phosphoinositide 3-kinase (PI3K)-dependent activation of Akt by growth factor receptor tyrosine kinases and G protein-coupled receptors. Increased expression of this gene and phosphorylation of the encoded protein may play a role in cancer metastasis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011]
Gene ID:	55704
Swiss prot ID:	Q3V6T2

Additional information:
Synonyms:	GTX55363; Akt phosphorylation enhancer; AKT-phosphorylation enhancer; APE; Coiled-coil domain-containing protein 88A; g alpha-interacting vesicle-associated protein; Girders of actin filament; girders of actin filaments; girdin; GIV; GRDN; HkRP1; Hook-related protein 1; KIAA1212; PEHO; PEHOL