GTX110231 ICC/IF Image
HDAC4 antibody [N3C1], Internal
GTX110231
Product group Antibodies
Overview
- SupplierGeneTex
- Product NameHDAC4 antibody [N3C1], Internal
- Delivery Days Customer9
- CertificationResearch Use Only
- Concentration2.1 mg/ml
- IsotypeIgG
- Scientific DescriptionHistones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class II of the histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. This protein does not bind DNA directly, but through transcription factors MEF2C and MEF2D. It seems to interact in a multiprotein complex with RbAp48 and HDAC3. [provided by RefSeq]
- Storage Instruction2°C to 8°C,-20°C
- UNSPSC12352203
References
- GluN2B/CaMKII mediates CFA-induced hyperalgesia via HDAC4-modified spinal COX2 transcription. Lai CY et al., 2018 Jun, NeuropharmacologyRead more
- Melatonin relieves neuropathic allodynia through spinal MT2-enhanced PP2Ac and downstream HDAC4 shuttling-dependent epigenetic modification of hmgb1 transcription. Lin TB et al., 2016 Apr, J Pineal ResRead more
- Modulation of Nerve Injury-induced HDAC4 Cytoplasmic Retention Contributes to Neuropathic Pain in Rats. Lin TB et al., 2015 Jul, AnesthesiologyRead more