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GTX84377 ICC/IF Image
GTX84377 ICC/IF Image
GTX84377 ICC/IF Image

HDAC6 antibody [4C5] - Overexpression Validated

Research Use Only
GTX84377
GeneTex
ApplicationsFlow Cytometry, ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityCanine, Human, Monkey, Mouse, Rat
Price on request
Packing Size
Large volume orders?
Order with a bulk request

Overview

  • Supplier
    GeneTex
  • Product Name
    HDAC6 antibody [4C5] - Overexpression Validated
  • Delivery Days Customer
    10
  • Applications
    Flow Cytometry, ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    4C5
  • Concentration
    0.84 mg/ml
  • Host
    Mouse
  • Isotype
    IgG
  • Scientific Description
    Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes (By similarity). Plays a central role in microtubule-dependent cell motility via deacetylation of tubulin.
  • Reactivity
    Canine, Human, Monkey, Mouse, Rat
  • Storage Instruction
    2°C to 8°C,-20°C
  • UNSPSC
    12352203

References

  • A protocol to visualize cytosolic aggresome-like bodies using confocal microscopy. Kim S et al., 2021 Sep 17, STAR Protoc
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  • Characterization of an apical ceramide-enriched compartment regulating ciliogenesis. He Q et al., 2012 Aug, Mol Biol Cell
    Read more
  • Clinacanthus nutans Protects Cortical Neurons Against Hypoxia-Induced Toxicity by Downregulating HDAC1/6. Tsai HD et al., 2016 Sep, Neuromolecular Med
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  • Primary cilia in stem cells and neural progenitors are regulated by neutral sphingomyelinase 2 and ceramide. He Q et al., 2014 Jun, Mol Biol Cell
    Read more
  • S100A11 Promotes Liver Steatosis via FOXO1-Mediated Autophagy and Lipogenesis. Zhang L et al., 2021, Cell Mol Gastroenterol Hepatol
    Read more
  • Therapeutic Effect of Modulating TREM-1 via Anti-inflammation and Autophagy in Parkinsons Disease. Feng CW et al., 2019, Front Neurosci
    Read more