GTX84377 ICC/IF Image
HDAC6 antibody [4C5] - Overexpression Validated
GTX84377
ApplicationsFlow Cytometry, ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityCanine, Human, Monkey, Mouse, Rat
Overview
- SupplierGeneTex
- Product NameHDAC6 antibody [4C5] - Overexpression Validated
- Delivery Days Customer10
- ApplicationsFlow Cytometry, ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone ID4C5
- Concentration0.84 mg/ml
- HostMouse
- IsotypeIgG
- Scientific DescriptionResponsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes (By similarity). Plays a central role in microtubule-dependent cell motility via deacetylation of tubulin.
- ReactivityCanine, Human, Monkey, Mouse, Rat
- Storage Instruction2°C to 8°C,-20°C
- UNSPSC12352203
References
- A protocol to visualize cytosolic aggresome-like bodies using confocal microscopy. Kim S et al., 2021 Sep 17, STAR ProtocRead more
- Characterization of an apical ceramide-enriched compartment regulating ciliogenesis. He Q et al., 2012 Aug, Mol Biol CellRead more
- Clinacanthus nutans Protects Cortical Neurons Against Hypoxia-Induced Toxicity by Downregulating HDAC1/6. Tsai HD et al., 2016 Sep, Neuromolecular MedRead more
- Primary cilia in stem cells and neural progenitors are regulated by neutral sphingomyelinase 2 and ceramide. He Q et al., 2014 Jun, Mol Biol CellRead more
- S100A11 Promotes Liver Steatosis via FOXO1-Mediated Autophagy and Lipogenesis. Zhang L et al., 2021, Cell Mol Gastroenterol HepatolRead more
- Therapeutic Effect of Modulating TREM-1 via Anti-inflammation and Autophagy in Parkinsons Disease. Feng CW et al., 2019, Front NeurosciRead more