Overview
- SupplierGeneTex
- Product NameHDAC6 antibody [N1], N-term
- Delivery Days Customer9
- CertificationResearch Use Only
- Concentration0.18 mg/ml
- IsotypeIgG
- Scientific DescriptionHistones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class II of the histone deacetylase/acuc/apha family. It contains an internal duplication of two catalytic domains which appear to function independently of each other. This protein possesses histone deacetylase activity and represses transcription. [provided by RefSeq]
- Storage Instruction2°C to 8°C,-20°C
- UNSPSC12352203
References
- A gene expression signature-based approach reveals the mechanisms of action of the Chinese herbal medicine berberine. Lee KH et al., 2014 Sep 17, Sci RepRead more
- Histone deacetylase 6 regulates estrogen receptor alpha in uterine leiomyoma. Wei LH et al., 2011 Aug, Reprod SciRead more
- Inhibition of HDAC3- and HDAC6-Promoted Survivin Expression Plays an Important Role in SAHA-Induced Autophagy and Viability Reduction in Breast Cancer Cells. Lee JY et al., 2016, Front PharmacolRead more