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GTX30105 WB Image
GTX30105 WB Image
GTX30105 WB Image

HIF1 alpha antibody [H1alpha67] - Orthogonal Validated

Research Use Only
GTX30105
GeneTex
ApplicationsGel Shift Assay, Flow Cytometry, ImmunoFluorescence, ImmunoPrecipitation, Western Blot, ChIP Chromatin ImmunoPrecipitation, ELISA, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin, Other Application
Product group Antibodies
ReactivityBovine, Ferret, Human, Mammals, Monkey, Mouse, Porcine, Primate, Rabbit, Rat, Sheep, Xenopus, Yeast
Price on request
Packing Size
Large volume orders?
Order with a bulk request

Overview

  • Supplier
    GeneTex
  • Product Name
    HIF1 alpha antibody [H1alpha67] - Orthogonal Validated
  • Delivery Days Customer
    10
  • Applications
    Gel Shift Assay, Flow Cytometry, ImmunoFluorescence, ImmunoPrecipitation, Western Blot, ChIP Chromatin ImmunoPrecipitation, ELISA, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin, Other Application
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    H1alpha67
  • Concentration
    1 mg/ml
  • Host
    Mouse
  • Isotype
    IgG
  • Scientific Description
    Hypoxia-inducible factor-1 (HIF1) is a transcription factor found in mammalian cells cultured under reduced oxygen tension that plays an essential role in cellular and systemic homeostatic responses to hypoxia. HIF1 is a heterodimer composed of an alpha subunit and a beta subunit. The beta subunit has been identified as the aryl hydrocarbon receptor nuclear translocator (ARNT). This gene encodes the alpha subunit of HIF-1. Overexpression of a natural antisense transcript (aHIF) of this gene has been shown to be associated with nonpapillary renal carcinomas. Two alternative transcripts encoding different isoforms have been identified. [provided by RefSeq]
  • Reactivity
    Bovine, Ferret, Human, Mammals, Monkey, Mouse, Porcine, Primate, Rabbit, Rat, Sheep, Xenopus, Yeast
  • Storage Instruction
    2°C to 8°C,-20°C
  • UNSPSC
    12352203

References

  • Fibrin patch influences the expression of hypoxia-inducible factor-1alpha and nuclear factor-kappaBp65 factors on ischemic intestinal anastomosis. Garcia-Vasquez C et al., 2018 Jun, Exp Biol Med (Maywood)
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  • Hypothermic neuroprotections in the brain of an echolocation bat, Hipposideros terasensis. Lin CL et al., 2017 Oct 18, Neuroreport
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  • Hypoxia-induced abrogation of contact-dependent inhibition of rheumatoid arthritis synovial fibroblast proliferation. Nonomura Y et al., 2009 Apr, J Rheumatol
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  • Hypoxia-inducible factor-1alpha and hypoxia-inducible factor-2alpha are expressed in kaposi sarcoma and modulated by insulin-like growth factor-I. Catrina SB et al., 2006 Aug 1, Clin Cancer Res
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  • Main histological parameters to be evaluated in an experimental model of myocardial infarct treated by stem cells on pigs. Garcia Gomez-Heras S et al., 2019, PeerJ
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  • Rapid and efficient generation of neural progenitors from adult bone marrow stromal cells by hypoxic preconditioning. Mung KL et al., 2016 Oct 7, Stem Cell Res Ther
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  • TNFalpha induces HIF-1alpha expression through activation of IKKbeta. Kuo HP et al., 2009 Nov 27, Biochem Biophys Res Commun
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