HIF1 alpha antibody - KO/KD, Comparison, Orthogonal, Overexpression Validated

Catalog number: GTX127309_100ul
Brand: GeneTex
Packing: 100 ul
Other sizes: 25 ul
Price: € 334.00
Expected delivery time: 10 days
Quantity:
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Product specifications for - HIF1 alpha antibody - KO/KD, Comparison, Orthogonal, Overexpression Validated

Overview: 
Product group: Antibodies
Category: Primary Antibodies
Application: ChIP Chromatin ImmunoPrecipitation; ImmunoCytoChemistry; ImmunoFluorescence; ImmunoHistoChemistry; ImmunoHistoChemistry Frozen; ImmunoHistoChemistry Parrafin; ImmunoPrecipitation; Western Blot
Species: Bovine, Human, Mouse, Rabbit, Rat
Host: Rabbit
Target: HIF1A
Target description: hypoxia inducible factor 1 subunit alpha
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Properties: 
Datasheet: Datasheet
  Research Use Only
UNSPSC: 12352203
Concentration: 0.37 mg/ml
Storage instructions: 2-¦C to 8-¦C, -20-¦C or -80-¦C
Scientific information: 
Scientific info: Hypoxia-inducible factor-1 (HIF1) is a transcription factor found in mammalian cells cultured under reduced oxygen tension that plays an essential role in cellular and systemic homeostatic responses to hypoxia. HIF1 is a heterodimer composed of an alpha subunit and a beta subunit. The beta subunit has been identified as the aryl hydrocarbon receptor nuclear translocator (ARNT). This gene encodes the alpha subunit of HIF-1. Overexpression of a natural antisense transcript (aHIF) of this gene has been shown to be associated with nonpapillary renal carcinomas. Two alternative transcripts encoding different isoforms have been identified. [provided by RefSeq]
Gene ID: 3091
Swiss prot ID: Q16665
Additional information: 
Synonyms: GTX_citation; ARNT interacting protein; ARNT-interacting protein; basic-helix-loop-helix-PAS protein MOP1; bHLHe78; class E basic helix-loop-helix protein 78; HIF1; HIF-1A; HIF-1alpha; HIF-1-alpha; HIF1-ALPHA; hypoxia inducible factor 1 alpha subunit; hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor); hypoxia-inducible factor 1 alpha isoform I.3; hypoxia-inducible factor 1-alpha; hypoxia-inducible factor1alpha; member of PAS protein 1; member of PAS superfamily 1; MOP1; PAS domain-containing protein 8; PASD8
ANGPTL1 Interacts with Integrin alpha1beta1 to Suppress HCC Angiogenesis and Metastasis by Inhibiting JAK2/STAT3 Signaling. Yan Q et al., 2017 Nov 1, Cancer Res Read more
A novel family of fluorescent hypoxia sensors reveal strong heterogeneity in tumor hypoxia at the cellular level. Erapaneedi R et al., 2016 Jan 4, EMBO J Read more
Acute intermittent hypoxia and rehabilitative training following cervical spinal injury alters neuronal hypoxia- and plasticity-associated protein expression. Hassan A et al., 2018, PLoS One Read more
Adenylate kinase hCINAP determines self-renewal of colorectal cancer stem cells by facilitating LDHA phosphorylation. Ji Y et al., 2017 May 18, Nat Commun Read more
Adverse early-life environment impairs postnatal lung development in mice. Lai PY et al., 2019 Sep 1, Physiol Genomics Read more
AHNAK2 is a Novel Prognostic Marker and Oncogenic Protein for Clear Cell Renal Cell Carcinoma. Wang M et al., 2017, Theranostics Read more
An Adaptation System to Avoid Apoptosis via Autophagy Under Hypoxic Conditions in Pancreatic Cancer Cells. Owada S et al., 2017 Sep, Anticancer Res Read more
Antitumor Activity of the Chinese Medicine JC-001 Is Mediated by Immunomodulation in a Murine Model of Hepatocellular Carcinoma. Chuang MH et al., 2017 Dec, Integr Cancer Ther Read more
Astaxanthin prevents ischemia-reperfusion injury of the steatotic liver in mice. Li S et al., 2017, PLoS One Read more
Autophagy-mediated adaptation of hepatocellular carcinoma cells to hypoxia-mimicking conditions constitutes an attractive therapeutic target. Owada S et al., 2018 Apr, Oncol Rep Read more