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GTX127309 WB Image
GTX127309 WB Image
GTX127309 WB Image

HIF1 alpha antibody

Research Use Only
GTX127309
GeneTex
Product group Antibodies
Price on request
Packing Size
Large volume orders?
Order with a bulk request

Overview

  • Supplier
    GeneTex
  • Product Name
    HIF1 alpha antibody
  • Delivery Days Customer
    9
  • Certification
    Research Use Only
  • Concentration
    1.48 mg/ml
  • Isotype
    IgG
  • Scientific Description
    Hypoxia-inducible factor-1 (HIF1) is a transcription factor found in mammalian cells cultured under reduced oxygen tension that plays an essential role in cellular and systemic homeostatic responses to hypoxia. HIF1 is a heterodimer composed of an alpha subunit and a beta subunit. The beta subunit has been identified as the aryl hydrocarbon receptor nuclear translocator (ARNT). This gene encodes the alpha subunit of HIF-1. Overexpression of a natural antisense transcript (aHIF) of this gene has been shown to be associated with nonpapillary renal carcinomas. Two alternative transcripts encoding different isoforms have been identified. [provided by RefSeq]
  • Storage Instruction
    2°C to 8°C,-20°C
  • UNSPSC
    12352203

References

  • ANGPTL1 Interacts with Integrin alpha1beta1 to Suppress HCC Angiogenesis and Metastasis by Inhibiting JAK2/STAT3 Signaling. Yan Q et al., 2017 Nov 1, Cancer Res
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  • A KDM6 inhibitor potently induces ATF4 and its target gene expression through HRI activation and by UTX inhibition. Kitajima S et al., 2021 Feb 25, Sci Rep
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  • A novel family of fluorescent hypoxia sensors reveal strong heterogeneity in tumor hypoxia at the cellular level. Erapaneedi R et al., 2016 Jan 4, EMBO J
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  • Acute intermittent hypoxia and rehabilitative training following cervical spinal injury alters neuronal hypoxia- and plasticity-associated protein expression. Hassan A et al., 2018, PLoS One
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  • Acute intermittent hypoxia enhances regeneration of surgically repaired peripheral nerves in a manner akin to electrical stimulation. Nadeau JR et al., 2021 Jul, Exp Neurol
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  • Adenylate kinase hCINAP determines self-renewal of colorectal cancer stem cells by facilitating LDHA phosphorylation. Ji Y et al., 2017 May 18, Nat Commun
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  • Adverse early-life environment impairs postnatal lung development in mice. Lai PY et al., 2019 Sep 1, Physiol Genomics
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  • AHNAK2 is a Novel Prognostic Marker and Oncogenic Protein for Clear Cell Renal Cell Carcinoma. Wang M et al., 2017, Theranostics
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  • An Adaptation System to Avoid Apoptosis via Autophagy Under Hypoxic Conditions in Pancreatic Cancer Cells. Owada S et al., 2017 Sep, Anticancer Res
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  • An mTORC1-GRASP55 signaling axis controls unconventional secretion to reshape the extracellular proteome upon stress. Nuechel J et al., 2021 Aug 19, Mol Cell
    Read more