HIF1AN antibody

GeneTex

HIF1AN antibody

9

Research Use Only

1 mg/ml

IgG

Hydroxylates HIF-1 alpha at Asp-803 in the C-terminal transactivation domain (CAD). Functions as an oxygen sensor and, under normoxic conditions, the hydroxylation prevents interaction of HIF-1 with transcriptional coactivators including Cbp/p300-interacting transactivator. Involved in transcriptional repression through interaction with HIF1A, VHL and histone deacetylases.

2°C to 8°C,-20°C

12352203