GTX108272 IHC-P Image
GTX108272 IHC-P Image
Histone H2A.X antibody
GTX108272
Product group Antibodies
Overview
- SupplierGeneTex
- Product NameHistone H2A.X antibody
- Delivery Days Customer9
- CertificationResearch Use Only
- Concentration0.81 mg/ml
- IsotypeIgG
- Scientific DescriptionHistones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene encodes a member of the histone H2A family, and generates two transcripts through the use of the conserved stem-loop termination motif, and the polyA addition motif. [provided by RefSeq]
- Storage Instruction2°C to 8°C,-20°C
- UNSPSC12352203
References
- A novel synthetic protoapigenone analogue, WYC02-9, induces DNA damage and apoptosis in DU145 prostate cancer cells through generation of reactive oxygen species. Chen HM et al., 2011 May 1, Free Radic Biol MedRead more
- Anti-cancer effect and gene modulation of ET-743 in human biliary tract carcinoma preclinical models. Peraldo-Neia C et al., 2014 Dec 5, BMC CancerRead more
- CNDAC-Induced DNA Double-Strand Breaks Cause Aberrant Mitosis Prior to Cell Death. Liu X et al., 2019 Dec, Mol Cancer TherRead more
- Ovatodiolide isolated from Anisomeles indica induces cell cycle G2/M arrest and apoptosis via a ROS-dependent ATM/ATR signaling pathways. Yu CY et al., 2018 Jan 15, Eur J PharmacolRead more
- Promotion of homology-directed DNA repair by polyamines. Lee CY et al., 2019 Jan 8, Nat CommunRead more
- Role of MRE11 in cell proliferation, tumor invasion, and DNA repair in breast cancer. Yuan SS et al., 2012 Oct 3, J Natl Cancer InstRead more
- The Thoc1 ribonucleoprotein and prostate cancer progression. Chinnam M et al., 2014 Nov, J Natl Cancer InstRead more
- Topoisomerase II Inhibitors Can Enhance Baculovirus-Mediated Gene Expression in Mammalian Cells through the DNA Damage Response. Liu MK et al., 2016 Jun 14, Int J Mol SciRead more