Iba1 antibody [HL22]
GTX635363
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetAIF1
Overview
- SupplierGeneTex
- Product NameIba1 antibody [HL22]
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500-1:3000. IHC-P: 1:100-1:1000. IHC-Fr: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDHL22
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID199
- Target nameAIF1
- Target descriptionallograft inflammatory factor 1
- Target synonymsAIF-1; allograft inflammatory factor 1; IBA1; interferon gamma responsive transcript; ionized calcium-binding adapter molecule 1; IRT1; IRT-1; protein G1
- HostRabbit
- IsotypeIgG
- Protein IDP55008
- Protein NameAllograft inflammatory factor 1
- Scientific DescriptionThis gene encodes a protein that binds actin and calcium. This gene is induced by cytokines and interferon and may promote macrophage activation and growth of vascular smooth muscle cells and T-lymphocytes. Polymorphisms in this gene may be associated with systemic sclerosis. Alternative splicing results in multiple transcript variants, but the full-length and coding nature of some of these variants is not certain. [provided by RefSeq, Jan 2016]
- ReactivityHuman, Mouse, Rat
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Sciatic nerve stimulation alleviates acute neuropathic pain via modulation of neuroinflammation and descending pain inhibition in a rodent model. Wong CE et al., 2022 Jun 15, J NeuroinflammationRead more
- JAK2/STAT3 pathway regulates microglia polarization involved in hippocampal inflammatory damage due to acute paraquat exposure. Fan Z et al., 2022 Mar 3, Ecotoxicol Environ SafRead more
- TRPV1 channel mediates NLRP3 inflammasome-dependent neuroinflammation in microglia. Zhang Y et al., 2021 Dec 14, Cell Death DisRead more
- Parecoxib alleviates the motor behavioral decline of aged rats by ameliorating mitochondrial dysfunction in the substantia nigra via COX-2/PGE2 pathway inhibition. Yan H et al., 2021 Aug 15, NeuropharmacologyRead more
- Effect of Sutellarin on Neurogenesis in Neonatal Hypoxia-Ischemia Rat Model: Potential Mechanisms of Action. Xiong LL et al., 2021, Am J Chin MedRead more
- Potential surrogate quantitative immunomodulatory potency assay for monitoring human umbilical cord-derived mesenchymal stem cells production. Teng SW et al., 2021 May, Cell Biol IntRead more