IgA (human) Matched Antibody Pair

Catalog number: REV-31-1030-MK-KI01
Brand: RevMAb Biosciences
Packing: 1 set
Price: € 592.00
Expected delivery time: 7 days
Sandwich ELISA using RM128 as the c...

Product specifications for - IgA (human) Matched Antibody Pair

Product group: Antibodies
Category: Antibody pairs, sets and duos
Application: ELISA
Species: Human
Datasheet: Datasheet
  Research Use Only
UNSPSC: 12352203
Storage instructions: -20-¦C
Scientific information: 
Scientific info: The Human IgA Matched Antibody Pairs is specific to Human IgA and has been demonstrated through ELISA. It does not cross-react to IgG from Non-Human Primate species (Rhesus and Cynomologus macaques), or mouse, rat or goat immunoglobulin. The kit can be used for the detection of therapeutic antibodies from samples obtained from experimental animals to provide accurate pharmacokinetic (PK) data. Immunoglobulin A (IgA) is an antibody isotype that plays a crucial role in the immune function of mucous membranes. IgA has two subclasses (IgA1 and IgA2) and can be produced as a monomeric as well as a dimeric form. The IgA dimeric form is the most prevalent and is also called secretory IgA (sIgA). sIgA is the main immunoglobulin found in mucous secretions, including tears, saliva, sweat, colostrum and secretions from the genitourinary tract, gastrointestinal tract, prostate and respiratory epithelium. It is also found in small amounts in blood. The secretory component of sIgA protects the immunoglobulin from being degraded by proteolytic enzymes; thus, sIgA can survive in the harsh gastrointestinal tract environment and provide protection against microbes that multiply in body secretions. In the blood, IgA interacts with the Fc receptor called FcalphaRI (or CD89), which is expressed on immune effector cells, to initiate inflammatory reactions.
Swiss prot ID: P01876, P01877
Safety information: 
Hazard information: Non-hazardous
Additional information: 
Synonyms: Ig alpha-1 chain C region; Ig alpha-1 chain C region BUR; Ig alpha-1 chain C region TRO; Ig alpha-2 chain C region; Ig alpha-2 chain C region BUT; Ig alpha-2 chain C region LAN