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InVivoMAb anti-mouse CD27

Research Use Only
BE0348
Bio X Cell
ApplicationsFlow Cytometry, ImmunoPrecipitation, Other Application
Product group Antibodies
ReactivityMouse
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Overview

  • Supplier
    Bio X Cell
  • Product Name
    InVivoMAb anti-mouse CD27
  • Delivery Days Customer
    7
  • Applications
    Flow Cytometry, ImmunoPrecipitation, Other Application
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    RM27-3E5
  • Concentration
    4-11 mg/ml
  • Estimated Purity
    >95%
  • Host
    Rat
  • Isotype
    IgG2a
  • Reactivity
    Mouse
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    12352203

References

  • CD4+ T Cell Help Confers a Cytotoxic T Cell Effector Program Including Coinhibitory Receptor Downregulation and Increased Tissue Invasiveness. Ahrends T et al., 2017 Nov 21, Immunity
    Read more
  • Agonistic CD40 mAb-Driven IL12 Reverses Resistance to Anti-PD1 in a T-cell-Rich Tumor. Ngiow SF et al., 2016 Nov 1, Cancer Res
    Read more
  • CD27 Agonism Plus PD-1 Blockade Recapitulates CD4+ T-cell Help in Therapeutic Anticancer Vaccination. Ahrends T et al., 2016 May 15, Cancer Res
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  • Control of established melanoma by CD27 stimulation is associated with enhanced effector function and persistence, and reduced PD-1 expression of tumor infiltrating CD8(+) T cells. Roberts DJ et al., 2010 Oct, J Immunother
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  • Anti-tumor effects of depleting and non-depleting anti-CD27 monoclonal antibodies in immune-competent mice. Sakanishi T et al., 2010 Mar 19, Biochem Biophys Res Commun
    Read more
  • CD27 and CD70 do not play a critical role in the development of experimental allergic conjunctivitis in mice. Sumi T et al., 2008 Aug 15, Immunol Lett
    Read more

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