InVivoMAb anti-mouse CD28

In vivo activation of Treg cells with a CD28 superagonist prevents and ameliorates chronic destructive arthritis in mice. Win SJ et al., 2016 May, Eur J Immunol

Induction of T regulatory cells by the superagonistic anti-CD28 antibody D665 leads to decreased pathogenic IgG autoantibodies against desmoglein 3 in a HLA-transgenic mouse model of pemphigus vulgaris. Schmidt T et al., 2016 Apr, Exp Dermatol

CD28 superagonist-mediated boost of regulatory T cells increases thrombo-inflammation and ischemic neurodegeneration during the acute phase of experimental stroke. Schuhmann MK et al., 2015 Jan, J Cereb Blood Flow Metab

Cutting edge: monovalency of CD28 maintains the antigen dependence of T cell costimulatory responses. Dennehy KM et al., 2006 May 15, J Immunol