InVivoMAb anti-mouse TIM-1 (CD365)

TIM-1 signaling is required for maintenance and induction of regulatory B cells. Yeung MY et al., 2015 Apr, Am J Transplant

TGF-beta-producing regulatory B cells induce regulatory T cells and promote transplantation tolerance. Lee KM et al., 2014 Jun, Eur J Immunol

Tim-1 blockade with RMT1-10 increases T regulatory cells and prolongs the survival of high-risk corneal allografts in mice. Tan X et al., 2014 May, Exp Eye Res

Targeting TIM-1 on CD4 T cells depresses macrophage activation and overcomes ischemia-reperfusion injury in mouse orthotopic liver transplantation. Zhang Y et al., 2013 Jan, Am J Transplant

Regulatory B cells are identified by expression of TIM-1 and can be induced through TIM-1 ligation to promote tolerance in mice. Ding Q et al., 2011 Sep, J Clin Invest